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Renal Colic clinical trials

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NCT ID: NCT06345716 Not yet recruiting - Renal Colic Clinical Trials

Paracetamol-Tramadol and Paracetamol-caffeine Versus Placebo in the Emergency Discharge Treatment of Renal Colic

RC
Start date: April 10, 2024
Phase: Phase 2
Study type: Interventional

This is a prospective, randomized, single-blind study. Patients included in the study after successful treatment of the acute attack were randomized upon discharge from the Emergency Department into three groups: oral paracetamol-tramadol group, oral paracetamol-caffeine group and oral placebo group.

NCT ID: NCT06342648 Not yet recruiting - Renal Colic Clinical Trials

Intracutaneous Sterile Water and Diclofenac Sodium Injections in Renal Colic

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

Renal colic is a serious and excruciatingly painful condition that frequently presents itself in the emergency department. In this trial, patients with renal colic who have received intramuscular diclofenac sodium injection or intracutaneous sterile water injection will have their Visual Analogue Scale (VAS) measured and compared.

NCT ID: NCT06276231 Not yet recruiting - Renal Colic Clinical Trials

Nebulized Salbutamol in Acute Renal Colic

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

A Prospective, double blinded, Randomized efficacy and safety trial of Nebulized Salbutamol in acute renal colic. Research Summary: INTRODUCTION: Pain is a common reason for individuals to seek health care, especially emergency care. Salbutamol has an effect for smooth muscle relaxation of the ureters. The administration of Salbuatmol has been shown to be safe and effective in the treatment of asthma exacerbation, but there have been no studies evaluating the use of neublized salbutamol for the treatment of acute renal colic pain in the emergency department. METHOD: This is a double blinded randomized clinical controlled trial. Two hundred renal colic patients presenting to the emergency department will be randomized to intervention (10 mg nebulized salbutamol) and (10 ml neublized Normal saline) case groups. Both the groups will get the standard treatment (IM diclofenac 75mg) added to the intervention. Their pain before and after intervention will be measured by Numerical Rating scale (NRS pain score). Patient and attending physician will be blinded throughout the study. The Secondry outcomes are safety, need for rescue medications and time to discharge. AIM: The aim of this study is to compare analgesic effects of Nebulized Salbutamol versus Placebo in adult patients with renal colic. PRIMARY OJECTIVES: Analgesic effects of Nebulized Salbutamol on the Numerical Rating scale (NRS). SECONDARY OBJECTIVES: Adverse Events, the need of rescue pain medications and time to discharge. PATEINT POPULATION: Adults (from age 18 to 60 years) who presents to emergency department (ED) at Armed force Hospital with acute flank pain suggestive of renal colic INTERVENTION: Single dose of Nebulized Salbutamol 10mg. CLINICAL MEASURMENT: Numerical pain Analog Scale will be assessed at 0,15,30, 45 and 60 minutes after intervention. Number and dosage of rescue medication, any reported events by patient or attending physician will be documented. OUTCOME: Decrease in pain measures by NRS pain score after Nebulized Salbutamol is given, tolerability and safety evaluation.

NCT ID: NCT06233643 Not yet recruiting - Renal Colic Clinical Trials

The Efficiency of Acupuncture Combined Intradermal Sterile Water Application in Acute Renal Colic

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the analgesic effect and tolerance profile of acupuncture combined with intradermal sterile water application versus intramuscular phloroglucinol in acute renal colic. In this study, we aimed primarily to test the efficacy of acupuncture combined with intradermal sterile water application as a rapid and effective treatment in severe renal colic. Participants will randomly divided into two groups. The first group received only intramuscular phloroglucinol, the second group received acupuncture and intradermal sterile water.The visual analog scale (VAS,ranging from 0 for no pain to 10 for maximum imaginable pain) was used to assess pain intensity at baseline and at 10, 20, 30, 45,and 60 minutes following the start of the treatment protocol. Possible treatment side effects were also recorded.

NCT ID: NCT06231043 Completed - Acute Renal Colic Clinical Trials

Diclofenac IM Versus Tramadol IV in Acute Renal Colic, RCT

Start date: April 27, 2022
Phase: Phase 4
Study type: Interventional

Patients presented with acute pain from renal colic, the standard of care are prescribed NSAIDs, most common drug used is intramuscular (IM) Diclofenac injected at the gluteal muscle. Due to adverse effects in some patients, the nursing council has banned the injection by nurses. Since then, there has been a change in treatment by using intravascular (IV) Tramadol. According to various research, Diclofenac has a higher efficacy in controlling pain compared to other medications. In clinical practice, Tramadol has less efficacy of decreasing pain and a longer onset of action. At presence, there has been no research performed comparing the efficacy between these two drugs especially from the viewpoint of time dimension.

NCT ID: NCT06176469 Recruiting - Urolithiasis Clinical Trials

Renal Colic and Urolithiasis in Poland

POLSTONE
Start date: December 1, 2023
Phase:
Study type: Observational

The aim of this study is to analyze the prevalence, effect on quality of life, and treatment-related behaviors for renal colic and urolithiasis in a population-representative sample of Poles. We will be using an Internet interview format for renal colic and urolithiasis evaluation. The study will include respondents representative for age and place of residence with adequate proportions of respondents from urban and rural areas.

NCT ID: NCT06026072 Completed - Renal Colic Clinical Trials

Validation of the CLAD Score Ifor Renal Colic Pain

CLAD-V
Start date: July 6, 2021
Phase: N/A
Study type: Interventional

Renal colic is a frequent reason for recourse representing 1 to 2% of emergency room admissions. This study would validate the performance of the CLAD score in predicting the need for surgical management within 7 days of patients admitted to the emergency department for renal colic pain.

NCT ID: NCT05776953 Recruiting - Analgesia Clinical Trials

Evaluation of the Effects of Ketorolac Dose on Duration of Analgesia in Emergency Department (ED) Renal Colic Patients

Start date: December 21, 2023
Phase: Phase 4
Study type: Interventional

This is a prospective interventional study examining the effect of ketorolac at doses of 15mg versus 30 mg for duration of analgesia in emergency department patients with suspected renal colic.

NCT ID: NCT05722782 Recruiting - Renal Colic Clinical Trials

Oral NSAI Versus Acetaminophen or Placebo as a Discharge Treatment of Non Complicated Renal Colics

NAP-RC
Start date: July 1, 2023
Phase: Phase 2
Study type: Interventional

Treatment with NSAI in renal colics has not been well investigated and there is no clear recommendations regarding this subject. The aim of this study is to determine if an oral NSAI treatment is beneficial in patients discharged for the emergency department after the first line treatment of a renal colic investigating the reccurence of pain, the reconsultation rates and the admissions.

NCT ID: NCT05653401 Completed - Renal Colic Clinical Trials

Treatment of Renal Colic in the Emergency Department: Comparison Between Magnesium Sulfate and Lidocaine.

Start date: November 20, 2022
Phase: Phase 2
Study type: Interventional

Rate of Intravenous Magnesium Sulfate Vs Lidocaine to treat Renal Colic in the Emergency Department.