Renal Colic Clinical Trial
Official title:
Comparing the Efficacy of Intravenous Paracetamol and Ketoprofen When Treating Renal Colic in Emergency Situations: a Randomized, Bi-centric, Double-blind Controlled Trial
The main objective of this study was to demonstrate the non-inferiority of intravenous paracetamol relative to intravenous ketoprofen when treating renal colic in an emergency ward. Efficacy is measured by the change in verbal numeric scale (vns) for pain at 30 minutes.
The secondary objectives of this study are:
- To compare the efficacy (non-inferiority) of intravenous paracetamol and ketoprofen at
90 minutes (vns for pain).
- To compare both arms in terms of other administered drugs (for pain).
- To observe and compare side effects between the two arms: cutaneous manifestation,
edema, bronchospasm, nausea, vomiting, headache, palpitation, chest pain, dizziness,
disturbance of consciousness, dyspnea, acute retention of urine.
- To determine predictors for the use of intravenous morphine when treating renal colic.
- To compare hospitalization rates between the two groups.
- To compare patient satisfaction concerning care between the two groups (vns for
satisfaction)
- To observe and compare changes towards complicated renal colic (obstructive
pyelonephritis, hyperalgesia, urinary tract rupture, need for surgical drainage, sepsis,
death)
;
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