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Efficacy of Nefopam and Morphine in Balanced Analgesia for Acute Ureteric Colic

Renal Colic Clinical Trial

Official title:
A Single Center, Prospective Randomized Double-blind Trial: Efficacy of Nefopam and Morphine in Balanced Analgesia for Acute Ureteric Colic

Clinical Trial Summary

This study is to see whether the combination regimen of ketorolac and nefopam is superior to that of ketorolac and morphine in controlling ureter stone-related acute flank pain.

Clinical Trial Description

The balanced analgesia regimen using both ketorolac and morphine is the most effective choice in controlling urolithiasis related acute pain. Previous animal and human studies reported that combination regimen of ketoprofen and nefopam showed synergistic effect in pain control. We hypothesized that using nefopam instead of morphine for ketorolac based combination analgesia will produce similar pain reduction without causing opioid-related side effect. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01543165
Study type Interventional
Source Seoul National University Hospital
Contact Kyuseok Kim, MD
Phone 82-31-787-3049
Email dremkks@snubh.org
Status Recruiting
Phase Phase 4
Start date December 2012
Completion date December 2013
View Details
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