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A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma Clinical Trial

Official title:
A Randomized Open Label Phase II Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Patients With Previously Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

Clinical Trial Summary

This study will evaluate the efficacy, safety, and pharmacokinetics of tobemstomig (also known as RO7247669) in combination with axitinib alone or with tiragolumab (anti-TIGIT) and axitinib, as compared to pembrolizumab and axitinib in participants with previously untreated, unresectable locally advanced or metastatic clear-cell renal cell carcinoma (ccRCC).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05805501
Study type Interventional
Source Hoffmann-La Roche
Contact Reference Study ID Number: BO43936 https://forpatients.roche.com
Phone 888-662-6728
Email global-roche-genentech-trials@gene.com
Status Recruiting
Phase Phase 2
Start date April 21, 2023
Completion date March 31, 2026
View Details
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