Clinical Trials Logo
  1. Home
  2. Renal Calculi
  3. NCT02734914

Suctioning Flexible Ureteroscopy With Intelligent Control of Renal Pelvic Pressure

Renal Calculi Clinical Trial

Official title:
Safety and Efficacy of Suctioning Flexible Ureteroscopy With Automatic Control of Renal Pelvic Pressure : A Clinical Randomized,Controlled Study

Clinical Trial Summary

This study evaluates the safety and efficacy of the suctioning flexible ureteroscopy(SF-URS) with automatic control of renal pelvic pressure for the treatment of upper urinary calculi using a prospective, randomized design. Half of participants will receive suctioning flexible ureteroscopy with automatic control of renal pelvic pressure, while the other half participants will receive retrograde intrarenal surgery using the classic flexible ureteroscopy.

Clinical Trial Description

Retrograde intrarenal surgery using flexible ureteroscope has become the first-line treatment for renal calculi < 3.0 cm and is recommended by the European Association of Urology due to its minimally-invasive nature and satisfactory result.

However, high perfusion rate leads to renal pelvic pressure increase, resulting in absorption of liquid, bacteria, and endotoxin into blood, followed by short-term complications such as systemic inflammatory response syndrome(SIRS , 8.1%), sepsis (0-4.5%), renal pelvic and ureteral tumor spread, and long-term complication of renal function impairment. Currently the commonly used flexible ureteroscope sheath (ureteral access sheath, UAS) reduces the renal pelvic pressure to a certain extent, but still can not control and monitor the renal pelvic pressure to reduce the incidence of complications, which, limit the clinical application of ureteroscopy.

Recently, the investigators present a novel technique of SF-URS with automatic control of renal pelvic pressure. In this study, transverse comparison is designed to evaluate the safety and efficacy of the suctioning flexible ureteroscopy with automatic control of renal pelvic pressure for the treatment of renal calculi. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02734914
Study type Interventional
Source The Affiliated Ganzhou Hospital of Nanchang University
Contact
Status Not yet recruiting
Phase N/A
Start date May 2016
Completion date August 2018
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT01450566 - Intraureteral Lidocaine for Post-Ureteroscopy Pain N/A
Recruiting NCT05701098 - SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD) N/A
Not yet recruiting NCT01008267 - Shockwave Lithotripsy (SWL) Under Selective, General Anesthesia. N/A
Completed NCT00250406 - Assessment of Drug-eluting Ureteral Stent on Bacterial Adherence and Biofilm Formation Phase 2
Recruiting NCT00169806 - Randall's Plaque Study: Pathogenesis and Relationship to Nephrolithiasis N/A
Completed NCT00169741 - Renogram Study With Percutaneous Nephrolithotomy (PERC): Alterations in Renal Blood Flow as a Consequence of PERC N/A
Completed NCT05972408 - Evaluation of Prevalence, Molecular and Genetic Backgrounds of Calcium-Based Stones Among Patients With Renal Calcular Disease in Mansoura Urology and Nephrology Center
Enrolling by invitation NCT02408211 - Preoperative Antibiotic PNL Study Phase 4
Completed NCT01437904 - A Pilot Study Assessing The Feasibility Of Outpatient Tubeless Percutaneous Nephrolithotomy (PCNL) N/A
Completed NCT00857090 - Pharmacokinetic, Safety and Efficacy Study of OMS201 in Subjects Undergoing Retrograde Ureteroscopic Removal of Upper Urinary Tract Stones Phase 1/Phase 2
Recruiting NCT05240170 - RIRS for Treatment of Stones in Congenital Anomalous Kidneys N/A
Completed NCT03112499 - The Effect of Three Endourological Procedures for the Management of Renal Calculi Regarding Acute Kidney Injury N/A
Recruiting NCT03206515 - The 18F Peel-way Sheath Versus the 18F Access Sheath With a Suction-evacuation Function MPCNL for the Management of 2-5cm Size Kidney Stones N/A
Completed NCT03344107 - Stent-related Symptoms Comparison: Polaris Loop vs Vortek Double-J Stents N/A
Recruiting NCT05077007 - Evaluation of Renal Damage After PCNL and ESWL Using Novel RNA Based Biomarkers N/A
Completed NCT03614247 - Cost-Effectiveness of Different Treatment Options for Lower Calyceal Stones N/A
Recruiting NCT05739812 - The Efficacy and Safety of Chinese Domestic Surgical Robot System in Urological Telesurgery N/A
Recruiting NCT05869890 - Ureteroscopic Laser Modality on Total Lasing Time and Total Energy in Patients With Large, Dense Renal Calculi N/A
Completed NCT00893282 - Clinical Evaluation of BackStop in Patients Undergoing Intraureteric Stone Lithotripsy N/A
Completed NCT00169715 - Database and Registry for Renal Diverticulum N/A