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Healthy Volunteer Study Comparing Tablet and Oral Solution Formulations

Relative Bioavailability Clinical Trial

Official title:
A Two-Part, Open-Label, Crossover, Bioavailability Study Comparing Tablet and Oral Solution Formulations of BLD-0409 in Healthy Volunteers

Clinical Trial Summary

A Two-Part, Open-Label, Crossover, Bioavailability Study Comparing Tablet and Oral Solution Formulations of BLD-0409 in Healthy Volunteers

Clinical Trial Description

The study will evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of two oral formulations of BLD-0409, tablet and solution, in healthy volunteers (HV). The study consists of two parts: Part 1: A randomized, open-label, 3-period, 6-sequence, complete crossover study with at least 3-day washout between treatment periods comparing oral solution formulation to tablet formulation. Part 2: A randomized, open-label, 4-period, 4-sequence, complete crossover study with at least 3-day washout between treatment periods evaluating single ascending doses of tablet formulation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04814472
Study type Interventional
Source Blade Therapeutics
Contact
Status Completed
Phase Phase 1
Start date May 16, 2021
Completion date November 3, 2021
View Details
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