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Clinical Trial Summary

This is a Phase 1b/2 open-label study to evaluate the safety/efficacy of MEDI-551 + MEDI0680 in participants with relapsed or refractory aggressive B-cell lymphomas who have failed 1-2 prior lines of therapy.


Clinical Trial Description

This is a Phase 1b/2, multicenter, open-label, study of MEDI-551 in combination with immunomodulating therapy evaluating the safety, tolerability, pharmacokinetics, immunogenicity and anti-tumor activity in subjects with relapsed or refractory aggressive B-cell lymphomas ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02271945
Study type Interventional
Source MedImmune LLC
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Status Completed
Phase Phase 1/Phase 2
Start date December 1, 2014
Completion date May 24, 2016