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Clinical Trial Summary

The primary purpose of this study is to identify the recommended Phase 2 dose(s) (RP2Ds) and schedule assessed to be safe for EMB-06 and to characterize the safety and tolerability of EMB-06 at the RP2Ds. Pharmacokinetics (PK), immunogenicity, and the anti-multiple myeloma activity of EMB-06 will also be assessed.


Clinical Trial Description

This is a Phase I/II, multi-center, open label, multiple-dose, first in human study, designed to assess safety and tolerability, and to identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) for EMB-06 in patients with relapsed or refractory multiple myeloma. Pharmacokinetics, pharmacodynamics, immunogenicity, and response will also be assessed. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04735575
Study type Interventional
Source Shanghai EpimAb Biotherapeutics Co., Ltd.
Contact Shuqi Zeng
Phone +8618621781427
Email shqzeng@epimab.com
Status Recruiting
Phase Phase 1/Phase 2
Start date May 20, 2021
Completion date March 1, 2025

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