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Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid Tumors

Refractory Solid Tumors Clinical Trial

Official title:
Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid Tumors

Clinical Trial Summary

This study is a single arm, pilot study of sirolimus in patient with Phosphatidylinositide-3-kinase (PIK3CA) mutation, PIK3CA amplification , PIK3CA-AKT pathway aberration Refractory solid tumor and/or specific sensitivity to mTOR inhibitors by Avatar scan that has progressed following standard therapy or that has not responded to standard therapy or for which there is no standard therapy. sirolimus 1mg will be administered orally daily. To investigate the efficacy and safety of sirolimus in patient with Refractory solid tumor.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02688881
Study type Interventional
Source Samsung Medical Center
Contact
Status Completed
Phase Phase 4
Start date February 5, 2017
Completion date February 24, 2021
View Details
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