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Refractive Errors clinical trials

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NCT ID: NCT04338880 Recruiting - Refractive Errors Clinical Trials

Academic Performance and Refractive Error

Start date: September 1, 2016
Phase:
Study type: Observational

Refractive errors constitute the leading cause of visual disability worldwide and that myopia progresses dramatically when students reach school age. Studies from different countries have reported inconsistent associations between educational outcomes and refractive errors. Therefore, our study aimed to assess the associations of high academic performance with ametropia prevalence and myopia progression in Chinese schoolchildren base on a multicohort observational design.

NCT ID: NCT04283331 Recruiting - Myopia Clinical Trials

Anesthetic Impregnated Bandage Soft Contact Lens (BSCL) in Pain Management After Photorefractive Keratectomy (PRK)

Start date: June 1, 2020
Phase: Phase 4
Study type: Interventional

Compared to laser-assisted in situ keratomileusis (LASIK), Photorefractive Keratectomy (PRK) is associated with more discomfort and requires more downtime. However, it is oftentimes considered the preferred method of refractive surgery for patients with dry eye syndrome, high refractive errors, thin corneas, or those with more active lifestyles who may be more prone to dislodging their LASIK flaps. We hypothesize that the use of bandage contact lenses soaked in proparacaine will decrease pain levels compared to solely the use of bandage contact lenses after PRK.

NCT ID: NCT04161326 Recruiting - Refractive Errors Clinical Trials

Environmental Health and Myopia Prevention and Control

Start date: January 1, 2016
Phase:
Study type: Observational

Myopia is one of the major causes of low visual acuity during childhood. It is generally more prevalent in urban areas than in rural areas. Current evidence does not address our understanding of the myopia incidence and development and associated risk geographic factors, such as green spaces. Therefore, our study aimed to evaluate the association between geographic factors and myopia base on a population-based large-scaled cohort design.

NCT ID: NCT04075591 Recruiting - Refractive Error Clinical Trials

Wavefront-guided LASIK for Monovision Treatment of Myopic Subjects With Presbyopia

Start date: September 24, 2019
Phase: N/A
Study type: Interventional

This study will be a 12-month, prospective, multicenter, open-label, non-comparative, non-randomized clinical investigation conducted at 8 to 14 sites. A total of 383 subjects will be enrolled to achieve approximately 268 treated subjects, resulting in at least 241 evaluable subjects at the point of refractive stability. After signing the informed consent, subjects meeting all inclusion and exclusion criteria in both eyes may be scheduled for surgery. The follow-up visit schedule will be the same for each operative eye.

NCT ID: NCT04044755 Recruiting - Refractive Errors Clinical Trials

Investigating the Effect of Using Myopia Prediction Algorithm on Myopia Children

Start date: August 3, 2019
Phase: N/A
Study type: Interventional

In this study, the investigators aim to perform a prospective, randomized controlled study to compare the myopia development between myopia children using myopia prediction algorithm and myopia children without using myopia prediction algorithm

NCT ID: NCT03789669 Recruiting - Refractive Error Clinical Trials

A Prospective, Multi-Center Evaluation of Corneal Flap Creation Using Cheetah Femtosecond Laser System and Cheetah Patient Interface

Start date: December 19, 2018
Phase: N/A
Study type: Interventional

The study is a 2-phase, prospective, open-label, comparative (phase II) study design that was chosen for the purpose of optimizing the Cheetah settings (phase I), and evaluating the Cheetah system quality of LASIK flap (phase II).

NCT ID: NCT03552016 Recruiting - Refractive Errors Clinical Trials

Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure

Start date: October 10, 2018
Phase: Phase 2
Study type: Interventional

The investigators plan on using riboflavin (a Vitamin that can easily be taken orally each day) and having the children involved in the study play outside (where there is UV light created by the sun) in order to prevent the eye from becoming progressively more near-sighted.

NCT ID: NCT03455478 Recruiting - Clinical trials for Blindness,Visual Impairment, Refractive Error, Cataract, High Myopia, Aging

Shanghai Eye Study for Adults

SESA
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

Blindness and visual impairment severely impact the visual health and life quality of people, particularly the 2.566 million senior citizens aged at 65 and above in Shanghai. The main reason is uncorrected refractive error, of which, 62.1% can be solved through refractive correction. For this reason, the uncorrected refractive errors of 154,000 senior citizens in Shanghai can be taken as a priority among the public health issues to prevent blindness. Now, with the aim to reduce the prevalence rate of blindness and visual impairment, it is planned to establish a public health service mechanism in terms of refractive error screening and correction for the elderly by relying on Shanghai's three-level (city-district-community) eye diseases prevention network, using proper refractive correction technology, and moving related services forward to communities in order to screen, identity, and correct blindness and visual impairment caused by refractive errors as early as possible.

NCT ID: NCT03419351 Recruiting - Refractive Errors Clinical Trials

Comparison of a Smartphone Based Self Refraction Tool With Conventional Refraction Error Estimation Methods

Start date: November 20, 2017
Phase: N/A
Study type: Interventional

Self evaluating tools based on smartphone devices are public available on the market for each person. The tools are used to estimate the existing refractive error for each eye of a patient. Hereafter, e.g. ordering glasses via internet could be the next step for this persons. The daily routine within an eye hospital shows, that estimation of the refractive error is a difficult and time consuming procedure. The study compares the results of the measured refractive error using a smartphone based tool with the results of conventional measurement methods.

NCT ID: NCT03030755 Recruiting - Keratoconus Clinical Trials

Corneal Elastography and Patient Specific Modeling

Start date: May 2016
Phase:
Study type: Observational

The goal of this research is to develop measurement tools and simulation technology for characterizing and predicting individual responses to corneal treatments and for advancing understanding of corneal ectasia risk factors. Patients who either 1) have keratoconus and are being evaluated for corneal crosslinking or 2) have refractive error and are being evaluated for refractive surgery procedures such as LASIK will have their eyes imaged to assess their mechanical properties and will have computational simulations performed to predict the response to treatment. One aim of the study is to test the hypothesis that computational models can predict the cornea's shape changes within clinically acceptable limits of error.