The Reflex Mechanism Underlying Neuromuscular Effects Of The Whole Body Vibration

Reflex, Ankle, Decreased Clinical Trial

— WBV-IRM  

Official title:

The Reflex Mechanism Underlying The Neuromuscular Effects Of The Whole Body Vibration

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04516798
• Other study ID #: ISTANBULPMR
• Status: Completed
• Phase: N/A
• Start date: October 5, 2020
• Est. completion date: October 7, 2020

Study information

• Verified date: October 2020
• Source: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study was conducted to determine whether the spinal reflex mechanism underlying the neuromuscular effects of whole body vibration (WBV) is tonic vibration reflex. Local and whole body vibration reflex latencies were measured in young adult healthy volunteers.

Description:

A total of eight volunteers were included according to the inclusion and exclusion criteria. The subjects were vibrated while standing upright with the WBV device (PowerPlate® Pro5). The 30, 35 and 40 Hz WBVs were applied for thirty seconds for each frequency with an amplitude of 2 mm. In the same session, 100, 135 and 150 Hz local vibrations were applied to the right Achilles tendon for thirty seconds for each frequency. 100, 135 and 150 Hz local vibrations were then applied to the right heel for thirty seconds for each frequency with an interval of five seconds. Vibration stimuli were recorded accelerometers. Reflex muscle responses were recorded from the right soleus muscle at a sampling rate of 40 KHz. Recording electrodes were placed on the belly of the right soleus muscle and the ground electrode was placed on the right medial malleolus.

The data were recorded with the PowerLab device, the records were processed and analyzed offline from the LabChart program. After the EMG records are filtered and rectified, reflex latencies were measured by cumulative averaging method using the accelerometer records as triggers (Karacan I, Cakar HI, Sebik O, Yilmaz G, Cidem M, Kara S, Türker KS.A new method to determine reflex latency induced by high rate stimulation of the nervous system.Front Hum Neurosci.2014 Jul 18; 8: 536.doi: 10.3389 / fnhum.2014.00536). After determining the Achilles tendon vibration reflex latency and the reflex latency induced by WBV, it was compared with statistical methods.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 8
• Est. completion date: October 7, 2020
• Est. primary completion date: October 7, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 40 Years

Eligibility

Inclusion Criteria:

• Healthy

• Young adult (20-40 years old)

• Both gender

• Volunteer

Exclusion Criteria:

• Cardiac disorder (Rhythm / conduction disorder, Cardiac pacemaker, Ischemic heart disease)

• Finding or suspected active deep vein thrombosis,

• History of deep vein thrombosis and pulmonary embolism,

• Orthostatic hypotension

• Hypertension

• Presence of fracture in the lower limb

• Achilles Contractures

• Active inflammatory, rheumatological or infectious disease in the lower limb

• Peripheral nerve lesions such as polyneuropathy, radiculopathy in the lower limb

• Those with a history of Achilles tendinopathy / bursitis

• Those with a history of kidney stones

• Patients with dizziness and balance problems,

• Cases with lesions on the skin surface where electrodes were attached

• Those with communication-cooperation problems

• Having a history of panic attacks

Related Conditions & MeSH terms

• Reflex, Abnormal
• Reflex, Ankle, Decreased

Intervention

Other:
• vibration
local and whole-body vibration were applied

Locations

Country	Name	City	State
Turkey	Istanbul Physical Medicine Rehabilitation Training & Research Hospital	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

References & Publications (3)

Aydin T, Kesiktas FN, Baskent A, Karan A, Karacan I, Türker KS. Cross-training effect of chronic whole-body vibration exercise: a randomized controlled study. Somatosens Mot Res. 2020 Jun;37(2):51-58. doi: 10.1080/08990220.2020.1720635. Epub 2020 Feb 5. — View Citation

Karacan I, Cakar HI, Sebik O, Yilmaz G, Cidem M, Kara S, Türker KS. A new method to determine reflex latency induced by high rate stimulation of the nervous system. Front Hum Neurosci. 2014 Jul 18;8:536. doi: 10.3389/fnhum.2014.00536. eCollection 2014. — View Citation

Yildirim MA, Topkara B, Aydin T, Paker N, Soy D, Coskun E, Ones K, Bardak A, Kesiktas N, Ozyurt MG, Celik B, Onder B, Kilic A, Kucuk HC, Karacan I, Türker KS. Exploring the receptor origin of vibration-induced reflexes. Spinal Cord. 2020 Jun;58(6):716-723 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	reflex latency	The time between the vibration stimulus and the reflex muscle response triggered by it was defined as the latency.	during intervention, an average of 8 minutes