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Clinical Trial Summary

The purpose of this study is to evaluate the incidence rate and severity of pre-specified mirvetuximab soravtansine (MIRV)-related ocular treatment-emergent adverse events (TEAEs) and assess prophylaxis strategies in all participants (symptomatic and asymptomatic) undergoing prospective ophthalmic evaluation with recurrent ovarian cancer (participants with either platinum-sensitive ovarian cancer [PSOC] or platinum-resistant ovarian cancer [PROC]) with high folate receptor alpha (FRĪ±) expression.


Clinical Trial Description

Participants will be randomized (1:1) to 1 of 2 ocular adverse event (AE) risk mitigation strategy arms (primary prophylactic steroid eye drops versus primary prophylactic vasoconstricting eye drops). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06365853
Study type Interventional
Source ImmunoGen, Inc.
Contact ImmunoGen, Inc.
Phone 781-895-0600
Email 424medical@immunogen.com
Status Not yet recruiting
Phase Phase 2
Start date June 30, 2024
Completion date May 26, 2027

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