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Clinical Trial Summary

A single center,observational cohort study to explore the relationship between reproductive tract microbiota and pregnancy outcome in the patients accepted IVF/ICSI. To investigate whether there is a correlation between reproductive tract microbiota and IVF/ICSI outcomes. Whether there are differences in reproductive tract microbiota (such as vagina, follicular fluid, uterine cavity, etc.) in patients with different pregnancy outcomes.


Clinical Trial Description

A single center,observational cohort study will enroll 120 infertile participants and then divide them into 3 groups: 1)Male infertility;2)Recurrent implantation failure; 3)Recurrent spontaneous abortion. The study will last for 1 year and recruit participants in Reproductive medicine center of Peking university third hospital. Each participant will be followed up for at least 1 year. Collect samples and record information at the first month, then follow-up 2 months to record the pregnancy outcomes. DNA will be extracted from the samples and then have sequence to figure out the compositions of microbiota. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04293068
Study type Observational [Patient Registry]
Source Peking University Third Hospital
Contact Fen-Ting Liu, Bachelor
Phone 15625120620
Email 624603036@qq.com
Status Recruiting
Phase
Start date August 18, 2020
Completion date December 2021

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