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Clinical Trial Summary

The purpose of this study is to evaluate the efficacy and safety of Sintilimab in combination with Bevacizumab and Temozolomide in subjects with recurrent glioblastoma.


Clinical Trial Description

This is a phase 2,open-label, multicenter, single-arm study designed to evaluate the efficacy and safety of Sintilimab in combination with Bevacizumab and Temozolomide in subjects with recurrent glioblastoma. A total of 30 patients will be enrolled in the study and administered Sintilimab in combination with Bevacizumab and Temozolomide. The study treatment will be continued for up to 4 cycles and Sintilimab was maintained until a progression of disease or unacceptable toxicity is confirmed. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05638451
Study type Interventional
Source Zhujiang Hospital
Contact Junde Zhang, MD
Phone 13002087575
Email 13002087575@163.com
Status Not yet recruiting
Phase Phase 2
Start date January 1, 2023
Completion date December 30, 2024

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