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Clinical Trial Summary

The purpose of this study is to evaluate the safety, side effects and benefits of autologous tumor infiltrating lymphocytes (TIL) specific to personalized Neo-antigens in the treatment of patients with recurrent, metastatic and advanced solid tumors.


Clinical Trial Description

Adoptive cell transfer therapy that utilizes an autologous TIL manufacturing progress is originally developed by the NCI for the treatment of patients with recurrent, metastatic cervical cancer and liver cancer. TILs specific to personalized neo-antigens will be expended in vitro and given back to the patients through vein. A total of 20 patients will be enrolled in the single-arm, open label, interventional study. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03658785
Study type Interventional
Source Tongji Hospital
Contact Hui Wang, MD
Phone +8613995688388
Email huit71@sohu.com
Status Recruiting
Phase Phase 1/Phase 2
Start date April 28, 2020
Completion date December 31, 2025

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