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Regenerative Therapy With Autologous Stromal Vascular Fraction Derived Mesenchymal Stem Cells and Platelet-rich Plasma to Treat Complex Perianal Diseases

Perianal Fistula Clinical Trial

Official title:
Regenerative Therapy With Autologous Stromal Vascular Fraction Derived Mesenchymal Stem Cells and Platelet-rich Plasma to Treat Complex Perianal Diseases

Clinical Trial Summary

Consecutive patients with complex anal fistula were prospectively followed for 12 months. Routine MRI was performed before and at 4 and 12 months after surgery. Continence was assessed likewise using a validated questionnaire. Fistula were drained with setons prior surgery. SVF was harvested from subcutaneous abdominal fat and PRP from peripheral blood. Distal fistulectomy to the sphincter was performed and the wound left open, while the internal orifice was closed. SVF-PRP was injected around the fistula. Patients showered their excision wound until dry. Outcomes were reported as median & interquartile range (IQR)

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05709717
Study type Observational [Patient Registry]
Source Kantonsspital Winterthur KSW
Contact Michel Adamina, MD, PD, MSc, EMBA HSG
Phone +41522663376
Email michel.adamina@ksw.ch
Status Not yet recruiting
Phase
Start date January 25, 2023
Completion date January 31, 2024
View Details
See also
  Status Clinical Trial Phase
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