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Rectal Fistula clinical trials

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NCT ID: NCT04541238 Not yet recruiting - Anal Fistula Clinical Trials

Imaging Template for Reporting Anal Fistula

ITRAF
Start date: September 1, 2020
Phase:
Study type: Observational

Magnetic resonance imaging (MRI) is the most used diagnostic tool for pre-operative assessment of anal fistula. However, there is lack of standardization in reporting this investigation. Moreover, reports may miss a number of key information for surgical planning. The aim of this study is to assess the effectiveness, reproducibility, and acceptability of a new template for reporting anal fistula, which may favor standardization in clinical practice and inform surgical decision making.

NCT ID: NCT04418323 Recruiting - Clinical trials for Video Assisted Anal Fistula Treatment

Video-assisted Anal Fistula Treatment (VAAFT) Versus Fistula-tract Laser Closure (Filac) Versus Conventional Seton in the Management of Anal Fistula

Start date: June 16, 2020
Phase: N/A
Study type: Interventional

Anal fistula is a chronic inflammatory tract connecting an internal opening in the anal canal with one or more than one external openings in the perianal skin Aim of the work This prospective randomized control trial, we will compare video-assisted anal fistula treatment (Vaaft) and Fistula Laser closure (Filac) and conventional Seton as regards, recurrence rate as a primary outcome. Secondary outcome includes; operative and post-operative data, hospital stay, pain score, healing time, return to work and continence

NCT ID: NCT04377542 Active, not recruiting - Anal Fistula Clinical Trials

RCT on LIFT Versus Modified Parks Technique Versus Two-Stage Seton

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

LIFT is a sphincter-saving procedure that is based on the concept of secure closure of the internal opening and concomitant removal of infected cryptoglandular tissue in the intersphincteric plane. Modified Parks technique involves adequate drainage of the intersphincteric space by extending the internal anal sphincterotomy. Placement of seton in the fistula track has been used for a long time and is still being currently used. Drainage two-stage seton is used to promote adequate drainage of infection and can be employed as a definitive treatment of anal fistula. This present randomized study aimed to compare LIFT, modified Parks technique, and two-stage seton in treatment of complex anal fistula in terms of success of treatment and complication rates.

NCT ID: NCT04357210 Completed - Anorectal Fistula Clinical Trials

Anal Sphincter Reconstruction After High Recurrent Anorectal Fistula Excision

Start date: January 1, 2016
Phase:
Study type: Observational

A retrospective analysis of patients treated for recurrent posterior anorectal fistula, who previously had undergone radical excision of fistula-in-ano, was performed. Three types of surgical reconstruction were compared: fistulectomy with primary sphincteroplasty, muco-muscular advancement flap and full-thickness low rectum posterior semicircular mobilization.

NCT ID: NCT04351074 Completed - Clinical trials for Transsphincteric Anal Fistula

Ligation of Intersphincteric Track (LIFT) Versus Fistulectomy in Trans-sphincteric Anal Ffistula.

professor
Start date: March 1, 2018
Phase: N/A
Study type: Interventional

78 patients with transsphincteric fistula allocated into two groups group A underwent LIFT group B u nderwent fistulectomy , comparison between the outcome og both procedures

NCT ID: NCT04326907 Completed - Anal Fistula Clinical Trials

Treatment of Complex Anal Fistulas Using Centrifuged Adipose Tissue Containing Progenitor Cells

CAT
Start date: May 1, 2016
Phase: N/A
Study type: Interventional

In the treatment of complex anal fistulas transplant of freshly collected autologous adipose tissue mechanically fragmented or centrifuged adipose tissue (CAT) might be an alternative to in vitro expanded autologous or allogeneic adipose-derived stem cells, showing remarkable efficacy in diverse therapeutic indications. The aim of our study is to evaluate randomly the efficacy and safety of the use of CAT in the healing process of complex anal fistulas, except for Crohn's disease (CD) related fistulas.

NCT ID: NCT04319861 Completed - Recurrence Clinical Trials

Anal Fistula Plug, a Retrospective Study

Start date: August 1, 2008
Phase: N/A
Study type: Interventional

In this study, we retrospectively reviewed clinical data of patients who were treated with an anal fistula plug for trans-sphincteric anal fistulas, and evaluated the long-term therapeutic effect of an anal fistula plug and the risk factors impacting anal fistula healing. In addition, we assessed the effects of post-operative changes on anal function, as well as the risk factors affecting anal function.

NCT ID: NCT04310800 Recruiting - Anal Fistula Clinical Trials

LIFT-plug vs LIFT, a RCT Trial

LIFT 02
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

To validate the effect of Ligation of Intersphincteric Fistula Tract (LIFT) Versus LIFT-plug procedure for Anal Fistula Repair in 7 medical centers

NCT ID: NCT04215718 Completed - Fistula in Ano Clinical Trials

Fistulotomy With Marsupialization Versus Fistulectomy With Wound Sutures in Simple Anal Fistula

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

comparison between fistulectomy wound closure and fistulotomw wound marsupialization in treatment of simple anal fistula

NCT ID: NCT04190862 Recruiting - Anal Fistula Clinical Trials

E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas

Start date: January 22, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if endothelial cells derived from human umbilical vein are safe for use in conjunction with fistulotomy for the treatment of simple anal fistulas. Endothelial cells are a special kind of cell in the body that line the inside surface of blood vessels. The goal of the study is to evaluate the preliminary safety of human umbilical vein cells in anal fistula healing.