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Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer — REAL  

Rectal Carcinoma Clinical Trial

Official title:
Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer (REAL): A Multicenter Randomized Controlled Trial

Clinical Trial Summary

The purpose of this study is to evaluate the safety and oncological feasibility of robot-assisted surgery for mid/low rectal carcinoma compared with laparoscopic surgery.

Clinical Trial Description

Laparoscopic surgery as the treatment for colon cancer has been widely recognized. But its use for rectal cancer is still controversial. Previous trials have shown that although the long-term survival outcomes were similar, laparoscopic surgery did not reach the non-inferiority in terms of local tumor radical resection, compared with open surgery. Robotic techniques are considered to improve the quality of surgery with three-dimensional vision, stable camera platform and flexible robotic arms. Meta-analyses have shown that compared with laparoscopic surgery, robotic surgery could improve surgical quality in terms of open conversion, circumferential resection margin, postoperative complications, postoperative recovery, and quality of life, with similar long-term survival. However, these evidences mainly came from retrospective studies and small-scale randomized controlled trials with low quality. There still needs high-quality clinical trials to confirm the advantages of robotic surgery for rectal cancer. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02817126
Study type Interventional
Source Fudan University
Contact
Status Active, not recruiting
Phase N/A
Start date July 10, 2016
Completion date December 31, 2023
View Details
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