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Re-irradiation for Pelvic Recurrences in Rectal Cancer Patients — Re-RAD-I  

Rectal Cancer Clinical Trial

Official title:
External Beam Radiotherapy for Pelvic Recurrences in Rectal Cancer Patients Previously Treated With Radiotherapy

Clinical Trial Summary

This study investigates the potential benefit of re-irradiation of patients with locally advanced rectal recurrences, by a prospective phase II clinical, imaging and translational research study.

Clinical Trial Description

The overall purpose of this trial is to evaluate the efficacy of re-irradiation of patients with locally advanced rectal cancer (LRRC) recurrences who previously received pelvic irradiation. Patients with potentially resectable LRRC will be treated with hyperfractionated Intensity-Modulated Radiotherapy consisting of 40.8 Gy in 1.2 fractions twice daily with concomitant oral capecitabine followed by surgery, when feasible. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05816980
Study type Interventional
Source Aarhus University Hospital
Contact
Status Completed
Phase Phase 2
Start date January 2015
Completion date January 2023
View Details
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