The Anatomical Localization of the Inferior Mesenteric Artery in Relation to the Left Colonic Artery

Rectal Cancer Clinical Trial

Official title:

A Prospective, Observational Study of the Anatomical Localization of the Inferior Mesenteric Artery in Relation to the Left Colonic Artery During Laparoscopic Radical Surgery for Rectal Cancer

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05651971
• Other study ID #: 202201-18
• Status: Recruiting
• Start date: November 1, 2022
• Est. completion date: December 31, 2025

Study information

• Verified date: December 2022
• Source: Tang-Du Hospital
• Contact: Nan Wang, Dr
• Phone: 15719286297
• Email: wangnandoc[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

1. To observe and measure the distance between the origin of LCA (left colonic artery，LCA) and IMA (inferior mesenteric artery，IMA) root and the distance between IMA and IMV (inferior mesenteric vein，IMV) at the origin of LCA in rectal cancer patients. Statistical analysis of intraoperative measured data, on the basis of the original anatomical relationship, to achieve anatomical localization of quantitative and accurate, for the preservation of LCA laparoscopic radical resection of rectal cancer to provide a strong anatomical basis.

2. The operation time, 253 lymph node dissection time, intraoperative blood loss, postoperative anal exhaust time, postoperative feeding time, postoperative hospital stay, postoperative ischemic colitis rate and postoperative anastomotic leakage rate of patients with laparoscopic radical resection of rectal cancer with preservation of LCA were recorded. The surgical efficacy and clinical significance of laparoscopic radical resection of rectal cancer with preservation of LCA were evaluated.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 120
• Est. completion date: December 31, 2025
• Est. primary completion date: December 1, 2024
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• Pathological diagnosis of rectal cancer (T2-4a, N- / +, M0) ; Laparoscopic radical resection of rectal cancer and preservation of LCA Patients and their families agree to participate in the clinical study

Exclusion Criteria:

• Those who had a history of lower abdominal surgery and could not undergo laparoscopic surgery LCA vascular absence was found during operation combined with other malignant tumors pregnant or lactating patients Combined with severe mental illness Severe diseases of the blood system, coagulation dysfunction ; Preoperative assessment of heart, lung and brain function, unable to tolerate surgery.

Related Conditions & MeSH terms

• Rectal Cancer
• Rectal Neoplasms

Intervention

Behavioral:
• measurement group
Measurement of the distance between the origin of LCA (left colonic artery,LCA) and IMA (inferior mesenteric artery,IMA) root and the distance between IMA and IMV (inferior mesenteric vein,IMV) at the origin of LCA in rectal cancer patients

Locations

Country	Name	City	State
China	General Surgery Gastriontestinal Department, Tang-Du of Fourth Medical University	Xi'an	Shanxi

Sponsors (1)

Lead Sponsor	Collaborator
Tang-Du Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Distance between LCA and IMA	Measurement of the distance between the origin of LCA (left colonic artery,LCA) and IMA (inferior mesenteric artery,IMA) root	intraoperative
Primary	The distance from LCA to IMA and IMV	Measurement of the distance between IMA and IMV (inferior mesenteric vein,IMV) at the origin of LCA	intraoperative
Secondary	operation time	From the beginning of anesthesia to the patient leaving the operating room	intraoperative
Secondary	253 lymph node dissection time	Record the time required to dissection 253 lymph node	intraoperative
Secondary	intraoperative blood loss	Record intraoperative bleeding	intraoperative
Secondary	exhaust time	Record the time of patient's first exhausting time after operation	Within one week after operation
Secondary	postoperative feeding time	Record the time of the patient's first meal after operation	Within one week after operation
Secondary	postoperative hospital time	Record the days from surgery to discharge	Within two weeks after operation
Secondary	postoperative anastomotic leakage rate	Record the situation of patient's anastomotic leakage	One month after operation