Rectal Cancer Clinical Trial
Official title:
Neoadjuvant FOLFOXIRI Chemotherapy Versus CapeOX Chemotherapy for Local Advanced Rectal Cancer: An Open Label Randomized Controlled Phase III Trial
This is a phase III randomized controlled trial comparing the efficacy and safety of FOLFOXIRI versus CapeOX as neoadjuvant regimen in treating patients with middle and upper locally advanced (MRI T3-4 or N+) rectal cancer. This study aims to optimize the neoadjuvant therapy for patients with anus-preserving resectable locally advanced rectal cancer, so as to improve the prognosis of them. It remains unclear about whether FOLFOXIRI or CapeOX neoadjuvant chemotherapy is more effective for locally advanced rectal cancer.
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NCT number | NCT05201430 |
Study type | Interventional |
Source | Fudan University |
Contact | Tianan Guo |
Phone | +86-021-64035387 |
[email protected] | |
Status | Recruiting |
Phase | Phase 3 |
Start date | August 27, 2021 |
Completion date | July 2027 |
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