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NCT04496765 Clinical Trial

Early-onset Rectal Cancer

Rectal Cancer Clinical Trial

Official title:
Patients With Early-Onset Rectal Cancer Aged 40 Year or Less Have Similar Oncologic Outcomes to Older Patients Despite Presenting in More Advanced Stage; A Retrospective Cohort Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04496765
Other study ID # Mansoura2020
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2008
Est. completion date April 30, 2020

Study information
Verified date July 2020
Source Mansoura University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The present study aimed to review the characteristics and outcome of early-onset rectal cancer in a subset of Egyptian patients aged 40 years or less. Since the previous studies assessed this point of research in CRC overall, the investigators opted to focus upon rectal cancer alone since it may represent a separate category, distinct from colon cancer, in this age group with regards to presentation, tumor behavior, and outcome.

Recruitment information / eligibility
Status Completed
Enrollment 244
Est. completion date April 30, 2020
Est. primary completion date December 1, 2017
Accepts healthy volunteers No
Gender All
Age group 10 Years to 80 Years
Eligibility Inclusion Criteria:

- Patients of either gender aged 40 years or less who presented with rectal cancer of any stage were included to the study

Exclusion Criteria:

- patients with colon cancer or other gastrointestinal cancer and patients who were lost to follow-up.

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Total mesorectal excision
Radical resection of rectal cancer and draining lymph nodes

Locations
Country Name City State
Egypt Mansoura university hospital Mansourah Dakahlia

Sponsors (1)
Lead Sponsor Collaborator
Mansoura University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Local recurrence recurrence of rectal cancer within the anatomic vicinity of the pelvis 36 months after surgery
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