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NCT03151759 Clinical Trial

MMP-7 Modulation by Short and Long Term Radiotherapy in Rectal Cancer Patients

Rectal Cancer Clinical Trial

— MMP-7  

Official title:
Effect of Long and Short Radiotherapy on MMP-7 Levels in Rectal Cancer Treatment

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03151759
Other study ID # LU155-01
Secondary ID
Status Completed
Phase N/A
First received May 10, 2017
Last updated May 10, 2017
Start date November 6, 2002
Est. completion date March 16, 2007

Study information
Verified date May 2017
Source Region Skane
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To analyse the effects of radiation therapy on inflammation and matrilysin levels in rectal cancer patients.

Recruitment information / eligibility
Status Completed
Enrollment 77
Est. completion date March 16, 2007
Est. primary completion date March 16, 2007
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

Adenocarcinoma of the rectum, ability to understand written and oral information, written consent.

Exclusion Criteria:

Colon cancer, benign tumors, impaired general condition of patient, declining to participate in the study, synchronous colonic tumors, logistical reasons, inability to understand written and/or oral information, previous pelvic irradiation, ongoing immunosuppressive therapy, diabetes with systemic complications.

Study Design

Related Conditions & MeSH terms

Intervention

Radiation:
• Neoadjuvant radiotherapy
Neoadjuvant radiotherapy prior to rectal cancer surgery

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Region Skane

Outcome
Type Measure Description Time frame Safety issue
Primary Matrilysin levels Inflammatory markers 1 - 6 weeks
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