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Clinical Trial Summary

This study includes patients affected by advanced and resectable rectal adenocarcinoma. It provides an induction chemotherapy with FOLFOXIRI regimen plus Bevacizumab followed by Chemoradiotherapy plus Bevacizumab. Surgery with total mesorectal incision must be performed within 7-9 weeks after this last treatment. The protocol will be evaluate the disease free survival at two years. Translational analyses will be performed to show the presence of VEGF polymorphism, CD133 surface markers on colorectal CSCs.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03085992
Study type Interventional
Source Azienda Ospedaliero, Universitaria Pisana
Contact
Status Completed
Phase Phase 2
Start date March 2012
Completion date March 12, 2018

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