Rectal Cancer Clinical Trial
Official title:
Diagnostic Value of Whole-Body MRI Compared to FDG-PET-CT for Rectal Cancer Preoperative Staging, Before and After Neoadjuvant Treatment
The purpose of this study is to determine whether whole-body MRI (WB-MRI) accuracy is superior to FDG-PET-CT considered as the gold-standard for the staging of distant lesions of rectal cancer.
Rectal cancer is the second cause of mortality after lung cancer in industrialized countries
and represent 28% of colorectal carcinomas. Despite major improvements in diagnosis and
treatment made those last years,mortality and morbidity remains high, because of high
prevalence of metastasis and local recurrence. A accurate initial staging is of paramount
importance for an appropriate treatment (neoadjuvant chemiotherapy and radiotherapy,
surgery).
Actually, there is no international consensus concerning imaging for the staging of rectal
cancer and modalities used are variable from one center to another.
WB-MRI represented a attractive and promising technique for the staging of rectal cancer,
free of ionizing radiation .
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