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Neoadjuvant Chemoradiation With Bevacizumab for Chinese Rectal Cancer Patients — New Beat  

Rectal Adenocarcinoma Clinical Trial

Official title:
Phase II Trial of Neoadjuvant Chemoradiation With Bevacizumab for Chinese Locally Advanced Rectal Adenocarcinoma

Clinical Trial Summary

The purpose of the study is to evaluate the efficacy and safety of the combination of cytotoxic chemotherapy (Oxaliplatin and 5Fu) with bevacizumab concomitantly with radiotherapy as neoadjuvant treatment for patients with locally advanced but resectable rectal adenocarcinoma.

Clinical Trial Description

Primary endpoint: Pathological Complete Response Rate (pCR)

Secondary endpoint: Time to Relapse, disease free survival, overall survival and safety data ;

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01554059
Study type Interventional
Source Sixth Affiliated Hospital, Sun Yat-sen University
Contact
Status Completed
Phase Phase 2
Start date March 2012
Completion date August 2014
View Details
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