Endotracheal Intubation Clinical Trial
Official title:
Screen and Intervene: A Diagnostic Accuracy Study and A Randomized, Open-label, Controlled Trial for Postextubation Dysphagia
This clinical trial aims to test the validity of a two-item swallowing screen and to examine the effects of the Swallowing and Oral-Care (SOC) Program on resumption of oral intake, incidence of penetration and aspiration, and incidence of pneumonia in adult patients who successfully extubated after ≥ 48 hours of endotracheal intubation.
Endotracheal intubation is life-sustaining, but it may contribute to postextubation dysphagia (PED) increasing the risk of penetration, aspiration, and aspiration pneumonia. Up to 84% of extubated patients had PED and approximately 60% penetrated and aspirated that can lead to aspiration pneumonia. The aims of this three-year, two-stage study are: 1) In the first stage, the investigators develop a two-item swallowing screen involving oral stereognosis and cough reflex test for predicting the resumption of oral intake and feeding-tube dependence by using a diagnostic accuracy study method; 2) In the second stage, the investigators conduct a randomized, open-label, controlled trial design to examine the effect of a once-daily, 7-day SOC Program on resumption of oral intake, incidence of penetration and aspiration, and incidence of pneumonia in adult patients who successfully extubated after ≥ 48 hours of endotracheal intubation. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT06089187 -
Comparing Endotracheal Tube Cuff Pressure in Laparoscopic Abdominal Surgery: Saline vs. Air Inflation
|
N/A | |
| Completed |
NCT02395432 -
A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Difficult Airway
|
N/A | |
| Completed |
NCT02395445 -
A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Routine Airway Management
|
N/A | |
| Unknown status |
NCT01041066 -
Nicardipine Versus Labetalol During Intubation
|
N/A | |
| Recruiting |
NCT02395406 -
A Comparison of Tracheal Intubation Using the Totaltrack vs the Airtraq Laryngoscope in Difficult Airway Management
|
N/A | |
| Recruiting |
NCT02395419 -
A Comparison of Tracheal Intubation Using the Totaltrack vs the Airtraq Laryngoscope in Routine Airway Management
|
N/A | |
| Enrolling by invitation |
NCT02277015 -
Intubation During Pediatric Resuscitation
|
N/A | |
| Completed |
NCT01169467 -
Cerebral Perfusion Pressure Using Precedex and Other Sedatives
|
Phase 3 | |
| Completed |
NCT00620386 -
Endotracheal Intubation Using Bonfils Fibrescope Without Neuromuscular Blockade
|
Phase 2/Phase 3 | |
| Completed |
NCT05069844 -
Preoperative Gum Chewing for Different Durations to Prevent Sore Throat After Endotracheal Intubation
|
N/A | |
| Enrolling by invitation |
NCT05620108 -
Intubating Conditions of Neuromuscular Blockade
|
N/A | |
| Completed |
NCT02741921 -
Conventional Double-lumen Tube vs VivaSight DL
|
N/A | |
| Recruiting |
NCT02295657 -
Double Lumen Tube Intubation
|
N/A | |
| Completed |
NCT01488370 -
Comparison of 2 Laryngoscopes for Endotracheal Intubation in Children Younger Than 2 Years Old
|
N/A | |
| Recruiting |
NCT01006668 -
Sevoflurane Versus Propofol for Intubation in Neonatal Intensive Care
|
Phase 3 | |
| Recruiting |
NCT04483895 -
Comparison Between the Oro-Helical Length Technique and the 7-8-9 Rule in Determination of the Ideal Endotracheal Tube Insertion Depth in Neonates
|
N/A | |
| Completed |
NCT04141267 -
Inhaled Sedation Using the Anesthetic-conserving Device ( ANACONDA) in Prehospital Emergency Medecine.
|
||
| Completed |
NCT01490580 -
Premedication Trial for Tracheal Intubation of the NEOnate
|
Phase 2/Phase 3 | |
| Completed |
NCT03878797 -
The Depth of Endotracheal Tube Insertion
|
||
| Not yet recruiting |
NCT05495880 -
Forearm-Supported Head Extension to Decrease Dental Contact
|
N/A |