Pulp Necrosis Clinical Trial
Official title:
Discoloration After Revascularization Using Calcium Phosphosilicate Based Bioceramic vs Mineral Trioxide Aggregate in Necrotic Immature Permanent Anterior Teeth: A Randomized Clinical Trial
the objective of this study is to evaluate post operative pain after using Endosequence versus Mineral Trioxide Aggregate as coronal plug material in revascularization of non vital immature anterior teeth
The treatment of immature young permanent anterior teeth is challenging because in addition of the need of elimination of bacterial infection; the lack of natural apical constriction against which a suitable filling material can be placed is considered the main problem. In the past many different treatments have been proposed for immature permanent teeth with necrotic pulps such as:Custom fitting of filling materials like gutta percha, Periapical surgeries, apexification. The disadvantages of these treatments are: the compromised Crown/root ratio, possibility of vertical fracture. Pulp revascularization is dependent on the ability of residual pulp and apical and periodontal stem cells to differentiate. These cells have the ability to generate a highly vascularized and rich living tissue. MTA was chosen as coronal seal to be placed over the blood clot due its a biocompatibility, bio-inductivity. However, the disadvantages of MTA are: discoloration of the coronal dentine when placed in the canal and the difficult handling properties. Recently, a new bioceramic material has been introduced to the market, namely, EndoSequence which is bioactive, has antibacterial activity, less cytotoxic effect and similar antimicrobial properties, maintain color stability of the tooth when compared to MTA ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01976065 -
Regeneration of Pulp-Dentin Development in Teeth With Necrotic Pulps and Immature Roots
|
Phase 1 | |
| Active, not recruiting |
NCT03763110 -
Photo-Activated Disinfection Versus Triple-Antibiotic Paste for Management of Necrotic Young Permanent Anterior Teeth
|
N/A | |
| Completed |
NCT00881907 -
Tissue Characterization in Teeth Treated With a Regeneration Protocol
|
Phase 0 | |
| Recruiting |
NCT04313010 -
Effectiveness of Regenerative Endodontics Therapy for Single-rooted Mature Permanent Tooth With Pulp Necrosis
|
N/A | |
| Completed |
NCT03589560 -
Evaluation of Biodentine and Mineral Trioxide Aggregate in Revascularization of Non Vital Immature Anterior Teeth
|
N/A | |
| Not yet recruiting |
NCT03717337 -
Success Rate of Single Versus Two Visit Regenerative Treatment Protocol in Non Vital Mature Anterior Teeth
|
N/A | |
| Completed |
NCT01817413 -
Comparison of Two Dental Techniques Used to Treat Teeth Which Have Become Infected or Painful Following Trauma
|
Phase 4 | |
| Completed |
NCT03849222 -
Evaluation the Effect of Using of Apical Matrix With Apexification Procedure on Apical Healing of Necrotic Immature Teeth
|
Phase 2/Phase 3 | |
| Completed |
NCT00881491 -
Treatment Outcome With a Revascularization Protocol Using the Triple Versus Double Antibiotic Paste
|
Phase 0 |