Clinical Trial Details
— Status: Not yet recruiting
Administrative data
NCT number |
NCT03813433 |
Other study ID # |
pedodontic department cairo |
Secondary ID |
|
Status |
Not yet recruiting |
Phase |
N/A
|
First received |
|
Last updated |
|
Start date |
June 2023 |
Est. completion date |
November 2024 |
Study information
Verified date |
September 2021 |
Source |
Cairo University |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Interventional
|
Clinical Trial Summary
the objective of this study is to evaluate post operative pain after using Endosequence
versus Mineral Trioxide Aggregate as coronal plug material in revascularization of non vital
immature anterior teeth
Description:
The treatment of immature young permanent anterior teeth is challenging because in addition
of the need of elimination of bacterial infection; the lack of natural apical constriction
against which a suitable filling material can be placed is considered the main problem.
In the past many different treatments have been proposed for immature permanent teeth with
necrotic pulps such as:Custom fitting of filling materials like gutta percha, Periapical
surgeries, apexification. The disadvantages of these treatments are: the compromised
Crown/root ratio, possibility of vertical fracture.
Pulp revascularization is dependent on the ability of residual pulp and apical and
periodontal stem cells to differentiate. These cells have the ability to generate a highly
vascularized and rich living tissue.
MTA was chosen as coronal seal to be placed over the blood clot due its a biocompatibility,
bio-inductivity. However, the disadvantages of MTA are: discoloration of the coronal dentine
when placed in the canal and the difficult handling properties.
Recently, a new bioceramic material has been introduced to the market, namely, EndoSequence
which is bioactive, has antibacterial activity, less cytotoxic effect and similar
antimicrobial properties, maintain color stability of the tooth when compared to MTA