Pulp Exposure, Dental Clinical Trial
Official title:
Clinical and Histological Evaluation of Hesperidin Versus Mineral Trioxide Aggregate (MTA) as a Direct Pulp Capping Material: A Randomized Controlled Trial
Verified date | May 2024 |
Source | Cairo University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Direct pulp capping technique is one of the oldest known treatments for exposed pulp tissue, and there is a continuous requirement for the most efficient materials to be used in this approach. Successful pulp capping is the usual way to preserve the vitality of tooth and avoid root canal treatment or surgical tooth extraction.
Status | Completed |
Enrollment | 32 |
Est. completion date | March 30, 2024 |
Est. primary completion date | December 1, 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 35 Years |
Eligibility | Inclusion Criteria: - Good oral hygiene, - Sound wisdom teeth with closed apices with normal pulp vitality response - No periodontal disease or periapical lesions on periapical radiograph - Cooperative patients approving to participate in the study Exclusion Criteria: - Medically compromised participants - Evidence of parafunctional habits - Heavy smokers - Teeth with signs and symptoms of irreversible pulpitis or pulp necrosis - Severe periodontal problems or pathological periapical changes - Teeth with open apex or pulp calcification |
Country | Name | City | State |
---|---|---|---|
Egypt | Faculty of Dentistry Cairo University | Cairo |
Lead Sponsor | Collaborator |
---|---|
Cairo University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Success Rate (Clinical evaluation) | Teeth with vital pulp (numerical values with electric pulp tester) and absence of clinical signs/symptoms (Visual Analog Score for pain) as one reported value indicating clinical success rate (%) | after 12 weeks | |
Secondary | Histomorphometric analysis (Histologic evaluation) | Thickness of formed dentin bridge (µm) | after 12 weeks | |
Secondary | Histomorphometric analysis (Histologic evaluation) | Number of inflammatory cells in pulp (scores for Inflammation intensity/extensity) | after 12 weeks |
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