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Dental Pulp Exposure clinical trials

View clinical trials related to Dental Pulp Exposure.

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NCT ID: NCT06171776 Active, not recruiting - Deep Caries Clinical Trials

Evaluation of Conservative Management of Teeth With Deep Cavitated Carious Lesions

Start date: January 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to compare postoperative pain of calcium silicate cement and resin-based tricalcium silicate (TheraCal LC) versus chemically Cured Glass Ionomer cement (FujiXI) in conservative management of very deep carious lesions by selective caries removal

NCT ID: NCT05878158 Recruiting - Clinical trials for Pulp Exposure, Dental

Simvastatin Versus MTA in Pulpotomy of Immature Permanent Molars

Start date: April 1, 2023
Phase: Early Phase 1
Study type: Interventional

the study will be done to evaluate the clinical and digital radiographic success of simvastatin versus MTA in pulpotomy of immature permanent molars

NCT ID: NCT05812053 Recruiting - Clinical trials for Pulp Exposure, Dental

Comparative Evaluation of Eggshell Powder in Primary Teeth Pulpotomy

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

To assess & compare clinical & radiographic effects of Tea Tree Oil- Eggshell Powder and Biodentine as pulpotomy agents in primary teeth.

NCT ID: NCT05397964 Enrolling by invitation - Clinical trials for Pulp Exposure, Dental

Retrospective Evaluation of the Results of Direct Pulp Capping Treatment

Start date: March 15, 2024
Phase:
Study type: Observational

The aim of this retrospective study is to evaluate the vitality of teeth that had been treated with calcium hydroxide in direct pulp capping cases.

NCT ID: NCT04989036 Completed - Clinical trials for Pulp Exposure, Dental

Biodentine Vital Pulpotomy in Immature Molars

Start date: October 1, 2016
Phase: Phase 4
Study type: Interventional

This study aimed to evaluate the clinical and radiographic success of pulpotomy in cariously exposed vital immature first permanent molars using calcium hydroxide and calcium silicate-based material (Biodentine ™). After a 12 months postoperative period, Biodentine ™ proved very useful as a successful pulpotomy agent in young permanent teeth.

NCT ID: NCT04351048 Active, not recruiting - Clinical trials for Dental Caries, Dental Pulp Exposure

Stepwise and One Step Techniques In Deep Dentin Lesion

Start date: December 12, 2016
Phase: N/A
Study type: Interventional

This double blind, randomized, controlled clinical trial aimed to observe the success of stepwise (SW) and one step (OneS) excavation techniques in the management of deep dentin caries. Additionally, evaluation of glass ionomer cement (GIC) as temporary restorative was also performed. For this purpose, forty participants were selected among the routine patients coming to university clinic. A permanent tooth having caries lesions penetrating to 75 percentage or more of dentin of patient were included. Randomization to SW and OneS groups were organized by coin method. The periphery of the cavities including enamel-dentin junction was cleaned until reach to hard dentin. Afterwards, selective removal to soft dentin on the pulpal side of the cavities was applied manually excavation and covered with pure calcium hydroxide and zinc oxide eugenol cement. GIC was used for temporary filling. This process was implemented both the first stage excavation of SW and OneS groups. Clinical and radiographic evaluations were performed at 6 months according to clinical signs and symptoms and radiographic sings using Periapical Index (PAI). Besides, temporary restorations were evaluated according to the of Ryge/Modified USPHS criteria. Following this evaluation, on the SW group, the cavities was re-entered and selective removal was applied up to firm dentin and pulp-capping were applied as mentioned above. In OneS group, temporary restoration was reduced as a base. All of the cavities were permanently restored with resin composite. Whole procedure was completed at one centre by a specialist, and control sessions was performed two experienced experts. Participants and experts were blinded in this study.

NCT ID: NCT04330768 Not yet recruiting - Dental Caries Clinical Trials

Platelet Rich Fibrin(PRF) Injection for Treatment of Dental Pulp Exposure:Randomized Clinical Trial

Start date: March 2021
Phase: N/A
Study type: Interventional

platelet rich fibrin(PRF) obtained from patient from patient blood sample (before start of treatment)is injected in the site of exposure of exposure(intervention group) control group will receive normal pulp capping procedure by MTA follow up will be one year

NCT ID: NCT04052685 Active, not recruiting - Dental Caries Clinical Trials

Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions

Start date: November 28, 2018
Phase: N/A
Study type: Interventional

Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions. Recently, this strategy is termed as selective removal to firm dentin (SRFD) and seems to increase the potential risk of pulp exposure or loss of pulp vitality for deep caries lesions radiographically extending ¾ of dentin tissue. Alternatively, selective removal to soft dentine (SRSD) that refers to removal of caries tissue at the periphery of the cavity to firm dentin and remaining caries tissue detected as soft or leathery in proximity with the pulp might be a less invasive excavation method for deep caries lesions to maintain pulpal health. However, information on clinical advantages or disadvantages of SRSD and SRFD excavation methods is sparse and mostly rely on studies conducted for primary teeth. Moreover, clinical trials are needed to demonstrate the combined effect of carious removal strategies and calcium silicate-based materials. The aim of this study is comparison of clinical success rates of SRSD and SRFD techniques in posterior deep caries lesions. The primary outcome of the study is comparison of clinical success of SRSD and SRFD techniques by clinical and radiographic examination after 3 months, 6 months, 1 year and 2 years. The secondary outcome of the study is to investigate whether or not calcium silicate-based materials have an effect on the success rate of the treatment.

NCT ID: NCT03838068 Completed - Clinical trials for Pulp Exposure, Dental

Pulpotomy Technique Preserving Vitality of Traumatized Anterior Permanent Immature Teeth

Start date: January 18, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Aim of the study: To compare the clinical and radiographic outcomes of mineral trioxide aggregate (MTA) and Biodentine as vital pulp therapy materials (pulpotomy) preserving the vitality of traumatized immature anterior permanent teeth. Materials and Methods: fifty vital traumatized immature anterior permanent teeth exposed with symptomatic /asymptomatic pulpitis were included in the study according to inclusion criteria and were equally divided in two groups. Included teeth were randomly assigned to either a control group (MTA 25 teeth) or a test group (Biodentine 25 teeth). After conducting pulpotomy and covering pulp stumps with the MTA and Biodentine, treated teeth received permanent restorations. Blinded clinical and radiographic evaluations were performed at different time intervals (base line immediate postoperative, 6, 12 and 18 months) according to clinical and radiographic criteria of success. Data were recorded and analyzed.

NCT ID: NCT03631511 Completed - Clinical trials for Dental Pulp Exposure

Histological Evaluation of Hard Tissue Formation After Direct Pulp Capping With RetroMTA

RetroMTA
Start date: April 3, 2016
Phase: N/A
Study type: Interventional

This study presents a clinical and histological evaluation of human pulp tissue responses after direct capping using RetroMTA. Seven teeth were subjected to pulp exposure, direct capping with RetroMTA, and restoration with a composite resin. Seven months later, the teeth were clinically and radiographically evaluated. The teeth were then extracted and subjected to histological processing and evaluation.