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Construction and Evaluation of the Liquid Biopsy-based Early Diagnostic Model for Lung Cancer

Healthy Clinical Trial

Official title:
Construction and Evaluation of the Liquid Biopsy-based Early Diagnostic Model for Lung Cancer

Clinical Trial Summary

The purpose of this study is to detetct Circulating tumor cells(CTCs) and Cancer Associated Macrophage-Like cells (CAMLs) in patients with pulmonary nodules using a novel microfluidic CTC-detection system. Then construct an early diagnostic model for lung cancer.

Clinical Trial Description

Patients found pulmonary nodules by CT screening will be enrolled in this study prospectively. CTCs and CAMLs both are cancer specific biomarkers found in the peripheral blood of patients with solid tumors including lung cancer. Through detecting CTCs and CAMLs in healthy volunteers and patients with pulmonary nodules who undergo biopsy, determine the cut-off value of the test. Further analysis of the test specificity and sensitivity, and on this basis construct an early diagnostic model for lung cancer. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04156360
Study type Observational
Source Shanghai Pulmonary Hospital, Shanghai, China
Contact Yayi He, MD, PHD
Phone +862165115006
Email 2250601@qq.com
Status Not yet recruiting
Phase
Start date November 1, 2019
Completion date June 1, 2021
View Details
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