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Pulmonary Nodule clinical trials

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NCT ID: NCT05160571 Completed - Lung Cancer Clinical Trials

A Retrospective Multicenter Review to Evaluate the Performance of the Ion Endoluminal System in Sampling Pulmonary Lesions

Start date: November 1, 2021
Phase:
Study type: Observational

This study is a retrospective multi-center chart review of patients who underwent an attempted biopsy of one or more pulmonary lesion(s) with the Ion Endoluminal System with the aim of assessing the overall performance of the system.

NCT ID: NCT04805723 Completed - Pulmonary Nodule Clinical Trials

Effects of Surgery Types in Patients With Pulmonary Nodules

Start date: July 10, 2018
Phase: N/A
Study type: Interventional

The investigators aimed to compare the pre-post operative effects of video-assisted thoracoscopy surgery (VATS) and thoracotomy on pulmonary function, exercise capacity, physical activity level, respiratory and peripheral muscle strength, inspiratory muscle endurance, quality of life, fatigue, dyspnea perception and pain in patients with pulmonary nodules.

NCT ID: NCT04182815 Completed - Lung Cancer Clinical Trials

Transbronchial Biopsy Assisted by Robot Guidance in the Evaluation of Tumors of the Lung

TARGET
Start date: December 10, 2019
Phase:
Study type: Observational

This study is designed to evaluate clinical safety and diagnostic accuracy of the robotic-assisted bronchoscopy with biopsy performed with the Monarchâ„¢ Endoscopy Platform in a broad range of patients with pulmonary lesions.

NCT ID: NCT03731156 Completed - Clinical trials for Invasive Fungal Infections

Granulomatous Pneumocystis Pneumonia

NC
Start date: June 1, 2018
Phase:
Study type: Observational

The intra-alveolar form of Pneumocystis jiroveci pneumonia (PjP) is a common pathology in immunocompromised patients, particularly those infected with HIV. The diagnosis is based on the detection of Pj in a LBA. Intra-tissue granulomatous form (PGP) is a rare entity observed in non-HIV immunocompromised patients. In this case, the LBA is mostly non-contributory and the diagnosis is based solely on the detection of cysts on histological examination on biopsy of a pulmonary nodule. For many years, it has been clearly demonstrated that the use of a specific PCR clearly improves the biological diagnosis of PcP. However, in case of granulomatous form this method is not implemented because the diagnostic hypothesis is not mentioned. In 2018, two cases of PGP were diagnosed at 3-month intervals at Montpellier University Hospital Center. The diagnostic confirmation was obtained with PCR Pj. In this context the investigators will investigate the interest of implementing PCR Pj on biopsies on pulmonary nodules from hospitalized patients between 2015 and 2018. In all selected patients, histopathological aspect of the nodule was compatible with a PGP and, no other diagnosis has been confirmed (infectious, tumoral, inflammatory ...). Finally, 17 patients were selected to check retrospectively, if the presence of Pj could be at the origin of the pathology.

NCT ID: NCT00917137 Completed - Pulmonary Nodule Clinical Trials

Transbronchial Needle Aspiration in the Diagnosis of Peripheral Pulmonary Malignancy

Start date: July 2008
Phase: N/A
Study type: Observational

The main purposes of this study are to assess the performance characteristics of transbronchial needle aspiration (TBNA) in the diagnosis of peripheral pulmonary lesions, and to identify the predictor variables of a positive aspirate.

NCT ID: NCT00906503 Completed - Pulmonary Nodule Clinical Trials

Fludeoxyglucose F 18-PET/CT Scans in Patients Receiving Ultra Short-Term Dexamethasone For Lung Nodules

Start date: April 2009
Phase: Phase 1
Study type: Interventional

RATIONALE: Imaging procedures, such as fludeoxyglucose F 18 (FDG)-PET/CT scan, done before and after steroid therapy may help doctors assess a patient's response to treatment and help plan the best treatment. PURPOSE: This phase I trial is studying fludeoxyglucose F 18 PET scan performed before and after ultra short-term dexamethasone therapy to see how well it measures changes in nodules in patients with lung nodules.