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Pulmonary Emphysema clinical trials

View clinical trials related to Pulmonary Emphysema.

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NCT ID: NCT00137956 Terminated - Clinical trials for Chronic Obstructive Pulmonary Disease

Endobronchial Valve for Emphysema PalliatioN Trial (VENT) Cost-effectiveness Sub-Study

Start date: December 2004
Phase: Phase 3
Study type: Interventional

The purpose of the VENT Cost-Effectiveness Sub-Study is to gather healthcare utilization and quality of life information on patients enrolled in the VENT study in order to analyze the relative cost-effectiveness of the endobronchial valve implant procedure.

NCT ID: NCT00129584 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Endobronchial Valve for Emphysema Palliation Trial (VENT)

Start date: January 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of the Emphasys Endobronchial Valve (EBV) and procedure (with pulmonary rehabilitation) compared to optimal medical management (with pulmonary rehabilitation) in patients with heterogeneous emphysema.

NCT ID: NCT00123422 Completed - Pulmonary Disease Clinical Trials

Innovation in Pulmonary Rehabilitation

Start date: October 2005
Phase: N/A
Study type: Interventional

The purpose of this study was to compare the effect of exercise treatment combined with breathing retraining (a computerized feedback program), with exercise treatment combined with heliox (a helium and oxygen combination), with exercise only in patients with moderate to severe chronic obstructive pulmonary disease. This was an 8-week intervention study.

NCT ID: NCT00085852 Completed - Pulmonary Emphysema Clinical Trials

US 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study - Initial Formulation

Start date: April 2005
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether the Aeris Bronchoscopic Lung Volume Reduction (BLVR) System is safe in patients with advanced emphysema.

NCT ID: NCT00051792 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Yoga for Treating Shortness of Breath in Chronic Obstructive Pulmonary Disease (COPD)

Start date: January 2003
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of yoga in reducing shortness of breath in people with chronic obstructive pulmonary disease (COPD). Patients in this study must have moderate to severe COPD and be primarily limited by shortness of breath.

NCT ID: NCT00018525 Completed - Emphysema Clinical Trials

Lung Volume Reductions Surgery (LVRS) Study

Start date: October 2000
Phase: N/A
Study type: Interventional

The main objectives of this study are to see if a type of lung surgery, known as lung reduction surgery, in addition to standard medical treatment improves the quality of life, lung function, and reduces the high mortality associated with severe emphysema when compared to standard medical treatment alone. Another goal of this study is to better identify the patients most likely to benefit from this surgical treatment. The information obtained in this study is important because lung reduction surgery is being done in several centers around the country but its long term benefits, if any, over standard medical treatment, are not known.

NCT ID: NCT00000621 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Feasibility of Retinoic Acid Treatment in Emphysema (FORTE)

Start date: September 1999
Phase: Phase 2
Study type: Interventional

To conduct feasibility studies on the use of retinoids in the treatment of emphysema. Specific objectives are to identify optimal patient populations, retinoids, doses, dosing schedules, routes of administration, and outcome measures preparatory to conducting a larger, controlled, clinical trial on the efficacy of retinoid therapy in the management of emphysema.

NCT ID: NCT00000606 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

National Emphysema Treatment Trial (NETT)

Start date: December 1996
Phase: Phase 3
Study type: Interventional

To evaluate the long term efficacy, morbidity and mortality associated with medical therapy with lung volume reduction surgery (LVRS) as compared to medical therapy alone and to define patient selection criteria. The trial, conducted in conjunction with a patient registry, is supported by the NHLBI, the Centers for Medicare and Medicaid Services (CMS), and the Agency for Healthcare Research and Quality (AHRQ).

NCT ID: NCT00000573 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Emphysema: Physiologic Effects of Nutritional Support

Start date: January 1990
Phase: Phase 2
Study type: Interventional

To determine if enteral nutrition support (ENS) restores normal body weight and improves muscle strength, exercise performance, sensation of dyspnea, and quality of life in malnourished patients with chronic obstructive pulmonary disease.