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Clinical Trial Summary

This study is to build a microbiome cohort by collecting sputum and fecal samples every few months for three years from healthy smokers and chronic obstructive pulmonary disease (COPD) patients. The aim of this study is to analyze the composition of microbiome of various samples (e.g. sputum, feces) and describe the difference between healthy smokers and COPD patients.


Clinical Trial Description

After the introduction of the gut-lung axis theory, extensive studies revealed the diversity of microbiomes among healthy smokers and COPD patients form the respiratory samples or lung tissues. In the previous study, distinct difference in composition of microbiome in lung tissue between healthy smokers and COPD patients was reported. This study is to build a microbiome cohort by collecting sputum and fecal samples every few months for three years from healthy smokers and chronic obstructive pulmonary disease (COPD) patients who are being followed up by Asan Medical Center. The aim of this study is to analyze the composition of microbiome of various samples (e.g. sputum, feces) and describe the difference between healthy smokers and COPD patients. This study would help establishing gut-lung axis model in humans. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04336423
Study type Observational [Patient Registry]
Source Asan Medical Center
Contact Sei Won Lee, M.D. Ph.D.
Phone 82-2-3010-3990
Email iseiwon@gmail.com
Status Not yet recruiting
Phase
Start date April 6, 2020
Completion date December 31, 2023

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