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NCT00502398 Clinical Trial

Is There Intravascular Hemolysis in Patients With Pulmonary Hypertension?

Pulmonary Artery Hypertension Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00502398
Other study ID # RMC074490CTIL
Secondary ID
Status Recruiting
Phase N/A
First received July 15, 2007
Last updated October 14, 2007
Start date September 2007

Study information
Verified date October 2007
Source Rabin Medical Center
Contact Ben Fox, MRCP
Phone +972 3 937 7221
Email foxb@clalit.org.il
Is FDA regulated No
Health authority Israel: Clalit Health Services
Study type Observational

Clinical Trial Summary

Patients with hemolytic disorders (e.g. sickle cell anemia or thalassemia) are known to develop pulmonary hypertension. Hemolysis is where red blood cells are destroyed and their contents released into the circulation. It is thought that these red-cell contents cause constriction and thrombosis of the blood vessels in the lungs. Conversely, it is possible that patients with pulmonary hypertension have hemolysis.

In this study we will be drawing blood from a range of patients and normal controls for a panel of blood tests related to hemolysis.

Recruitment information / eligibility
Status Recruiting
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

One of the following four conditions :

- Pulmonary artery hypertension

- Obstructive sleep apnea with pulmonary hypertension

- Lung transplant candidates without pulmonary hypertension

- Normal Controls

Exclusion Criteria:

- Known hemolytic disorder

- Recent blood loss (<3 months)

- Recent blood transfusion (<3 months)

- Liver disease

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Intervention

Procedure:
• Blood test

Locations
Country Name City State
Israel Pulmonary Institute, Rabin Medical Center (Beilinson campus) Petach Tikva

Sponsors (1)
Lead Sponsor Collaborator
Rabin Medical Center

Country where clinical trial is conducted

Israel, 

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