Is There Intravascular Hemolysis in Patients With Pulmonary Hypertension?

Status Recruiting

Clinical Trial Summary

Patients with hemolytic disorders (e.g. sickle cell anemia or thalassemia) are known to develop pulmonary hypertension. Hemolysis is where red blood cells are destroyed and their contents released into the circulation. It is thought that these red-cell contents cause constriction and thrombosis of the blood vessels in the lungs. Conversely, it is possible that patients with pulmonary hypertension have hemolysis.

In this study we will be drawing blood from a range of patients and normal controls for a panel of blood tests related to hemolysis.

Clinical Trial Description

n/a

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00502398
Study type	Observational
Source	Rabin Medical Center
Contact	Ben Fox, MRCP
Phone	+972 3 937 7221
Email	foxb@clalit.org.il
Status	Recruiting
Phase	N/A
Start date	September 2007

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05056532` - Evaluation of Respiratory Muscle in Patient With Pulmonary Arterial Hypertension
Active, not recruiting	`NCT06003244` - High Altitude (HA) Residents With Pulmonary Vascular Diseases (PVD), 6 Minute Walk Distance (6MWD) Assessed at 2840m (HA) With and Without Supplemental Oxygen Therapy (SOT)	N/A
Active, not recruiting	`NCT06072417` - HA Residents With PVD, SDB Assessed at HA (2840m) vs LA (Sea Level)	N/A
Recruiting	`NCT02966665` - : Vascular Function in Health and Disease	Phase 1
Completed	`NCT04456998` - GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH)	Phase 2
Not yet recruiting	`NCT06035861` - Endothelial Cell Activation and Total Pulmonary Resistance in PAH	N/A
Recruiting	`NCT03138863` - Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO)	N/A
Recruiting	`NCT02102672` - Trimetazidine in Pulmonary Artery Hypertension	Phase 2
Withdrawn	`NCT06122922` - Xenon MRI in Stable Pulmonary Hypertension (Jupiter AUGEAN)	Phase 2
Recruiting	`NCT03195543` - Assessment of Blood Coagulation Disorders in Patients With Pulmonary Hypertension
Completed	`NCT04337671` - Impact of Aerobic Training on Sleep Quality and Aerobic Fitness in Male Patients With Pulmonary Artery Hypertension	N/A
Completed	`NCT03198910` - Retrospective Data Analysis of Data From the Zurich PH Registry
Completed	`NCT03979482` - Skeletal Muscle Mitochondrial Abnormalities and the Metabolic Syndrome in PAH
Active, not recruiting	`NCT05996302` - HA Residents With PVD, 6MWD Assessed at HA (2840m) vs LA (Sea Level)	N/A
Active, not recruiting	`NCT06084559` - HA Residents With PVD, Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) With and Without Supplemental Oxygen Therapy (SOT)	N/A
Withdrawn	`NCT02684786` - A Study of Stellate Ganglion Block and / or Reserpine in Group 2 Pulmonary Hypertension	Phase 1
Not yet recruiting	`NCT06258850` - REstoration of VItamin D in Pulmonary Arterial Hypertension	Phase 4
Completed	`NCT04094272` - Pulmonary Arterial Hypertension in Patients With Direct-Acting Antiviral Medications for Hepatitis C Virus Infection
Active, not recruiting	`NCT01763112` - Training With Whole Body Vibration Device in Patients With PAH	N/A
Completed	`NCT01581086` - Vascular Subphenotypes of Lung Disease in HIV & COPD	N/A