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Connectivity Changes Associated With Ketamine Assisted Psychotherapy for PTSD — CONCHKAP  

PTSD Clinical Trial

Official title:
Connectivity Changes Associated With Ketamine Assisted Psychotherapy for PTSD

Clinical Trial Summary

The goal of this clinical trial is to learn about the effects of Ketamine Assisted Psychotherapy [KAP] on individuals with Post Traumatic Stress Disorder [PTSD]. The main questions it aims to answer are: 1. Does KAP improve symptoms of PTSD? 2. What changes in brain network connectivity are seen with KAP?

Clinical Trial Description

A total of 14 adult patients with PTSD will be recruited from UNM outpatient clinics and undergo rsfMRI and behavioral assessment prior to ketamine treatment. They will complete baseline scan at day one, a preparatory session (initial part of KAP), IM ketamine treatment, then within 24 hours, an integration session to take advantage of neuroplasticity for optimal therapeutic progress. Each participant will have two complete KAP sessions (preparation, treatment, and integration) followed by rsfMRI within approximately 24 hours, and again approximately two weeks after the completion of the second KAP session. Patients will also have repeat clinical assessments after each treatment. Changes in PTSD symptoms will be correlated with changes in connectivity at each rsfMRI. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06036511
Study type Interventional
Source University of New Mexico
Contact
Status Withdrawn
Phase Phase 1/Phase 2
Start date December 31, 2023
Completion date December 31, 2023
View Details
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