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Clinical Trial Summary

The goal of this study is to investigate the effects of a single bout of aerobic exercise on neurophysiological indices of emotion regulation and cognitive control in individuals with clinically significant PTSD symptoms. In this proposed study, 50 adult females with clinically significant PTSD symptoms will be randomized into two groups: a 20-minute moderate-to-vigorous intensity aerobic exercise group, or a 20-minute silent sitting control group. Prior to and following the exercise/sitting session, participants will complete a letter flanker task and an emotion regulation picture viewing task while their electrical brain activity is continuously recorded via electroencephalogram (EEG). Utilizing a multimodal assessment approach, cognitive control will be measured using behavioral (i.e., accuracy, reaction time) and neurophysiology (i.e., error-related negativity; ERN). Emotion regulation will be measured using self-reported and neurophysiological indices of emotional reactivity (i.e., late positive potential; LPP).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05643716
Study type Interventional
Source Michigan State University
Contact Jason S Moser, Ph.D.
Phone 517-355-2159
Email jmoser@msu.edu
Status Recruiting
Phase N/A
Start date March 5, 2024
Completion date July 2025

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