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Clinical Trial Summary

This study aims to test whether aerobic exercise performed after fear extinction learning improves the consolidation and subsequent recall of the learned safety memories (i.e., fear extinction memories) among adult women with PTSD related to interpersonal violence exposure, and whether this effect is mediated by the ability of exercise to increase acute levels of Brain-Derived Neurotrophic Factor (BDNF) and endocannabinoids (eCB). Participants can expect to be on study for up to 90 days, participating in 4 study stages: Day 1 of Assessments, Day 2 of Fear Learning, Day 3 of Fear Extinction (and activity), and Day 4 of Recall of Fear Extinction.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04113798
Study type Interventional
Source University of Wisconsin, Madison
Contact
Status Completed
Phase N/A
Start date April 8, 2019
Completion date January 21, 2020

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