Psychotic Disorders Clinical Trial
Official title:
Cognitive Therapy for Distressing Visual Hallucinations: A Pilot Study
Verified date | October 2017 |
Source | Newcastle University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The study is a pilot study of Cognitive therapy for people with psychosis who have distressing visual hallucinations. The aim is to evaluate whether this is an acceptable, feasible and effective treatment. This is a pilot study and there is no randomisation to either CBT or treatment as usual (TAU). If a participant is allocated to the cognitive therapy plus TAU condition then the participant will meet with a therapist on initially a weekly basis and receive up to 8 sessions of CBT over a 2 month period. The participant will also have regular assessments conducted by a researcher who is independent to the treatment group. It is predicted that those people receiving CBT will improve on measures of symptoms, and particularly for measures of visual hallucinations.
Status | Completed |
Enrollment | 7 |
Est. completion date | December 2013 |
Est. primary completion date | December 2013 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 38 Years |
Eligibility |
Inclusion Criteria: - Meet entry criteria for Early Intervention in Psychosis (EIP) services - Distressing visual hallucinations - Age 18-38 years (the usual upper range of the EIP services) Exclusion Criteria: - Organic brain disease including dementia, epileptic psychosis, head injury (may be alternative cause of symptoms, or impair cognitive function and ability to do CBT) - Primary diagnosis of drug or alcohol misuse (as above) - Impaired intellect severe enough to interfere with ratings (as above) - In-patient/acute psychiatric care needed at baseline assessment (patients must be well enough to engage in out-patient CBT) - Previous CBT for psychosis (those previously exposed to the CBT model may be more likely to respond to CBT) |
Country | Name | City | State |
---|---|---|---|
United Kingdom | Early Intervention in Psychosis service | Sunderland | Tyne and Wear |
Lead Sponsor | Collaborator |
---|---|
Newcastle University | Northumberland, Tyne and Wear NHS Foundation Trust |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change from baseline in distress of visual hallucinations as assessed by the Psychotic symptoms rating scale for hallucinations (PSYRATS). | The PSYRATS measures distress, conviction and preoccupation and impact of life of symptoms such as voices or delusions. It has been adapted to be relevant to visual hallucinations. | change pre to post intervention which will be on average 3 months | |
Secondary | Change from baseline on measure of depression (Beck Depression Inventory) | The BDI is a short, reliable, widely used measure of depression/low mood. It is a self report measure and participants will be asked to complete it before and after the intervention | Baseline and at three months | |
Secondary | Change from baseline on measure of symptoms of psychosis as measured by he Schizophrenia Change Scale (SCS). The SCS is a subscale of the Comprehensive Psychopathological Rating Scale (CPRS), (Montgomery, Taylor, & Montgomery, 1978) | The SCS is a short, reliable, widely used measure of symptoms of psychosis. It is a interview based measure and participants will be asked to complete it before and after the intervention | baseline and at three months |
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