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Psychophysiologic Reaction clinical trials

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NCT ID: NCT06368297 Not yet recruiting - Clinical trials for Overweight and Obesity

The Effect of Ketone Ester Supplementation and Ketogenic Diet on Brain Plasticity in Overweight/Obese Adults

Start date: April 2024
Phase: N/A
Study type: Interventional

This project comprises an initial crossover placebo-controlled neurophysiological study to ascertain the effect of acute ketone ester ingestion on motor cortex plasticity, followed by a second 2-week intervention study aimed to compare the effect of a ketogenic diet versus ketone ester supplementation on motor cortex plasticity, resting brain function and structure, and metabolic and neuroendocrine responses.

NCT ID: NCT05913869 Recruiting - Mindfulness Clinical Trials

Online Mindfulness-based Program for Parents of Children With Autism

Start date: August 15, 2022
Phase: N/A
Study type: Interventional

The goal of the project is to investigate the effects of online 8-week MBSR intervention on diverse parents to support their children with ASD. The investigators will conduct a randomized waitlist-controlled trial with a sample size 22 parents. This study utilizes psychological, behavioral and psychophysiological measures with parents of children with ASD ages 6-12. The first aim is to determine if parents of children with autism from diverse populations are willing participate in and complete an online MBSR program and if online delivery is as effective as in-person program. The battery of parental-report psychological assessments to measure resilience, parental sleep and stress as well as children's behaviors will be administered before and after the treatment. The second aim is to investigate the effects of a virtual MBSR intervention on cardiovascular and sympathetic nervous activity measured by continuous EDA and EKG. Participants will participate in a validated laboratory stress protocol consisting of mental arithmetic and speech tasks before and after the MBSR intervention.

NCT ID: NCT05532839 Completed - Clinical trials for Psychophysiologic Reaction

Self-paced High-intensity Interval Training and Moderate Intensity Continuous Training in Young Adults

Start date: July 17, 2022
Phase: N/A
Study type: Interventional

Study will be randomized clinical trial. Data will be collected from non probability convenient sampling technique. Total 26 participants from Pakistan Sports Board will be selected and randomly allocated in two different groups i.e. Group A and Group B. Group A will be given high intensity interval training and Group B will be on moderate intensity continuous training. Statistical package for the social sciences will be used to analyze the results by using parametric test after confirming normality of data.

NCT ID: NCT05516355 Completed - Stress Clinical Trials

Psychological and Neurobiological Impact of a Retreat Based on Mindfulness and Compassion for Stress Reduction.

Retreat
Start date: July 1, 2022
Phase: N/A
Study type: Interventional

The study is aimed at comparing the differential effects of two widely used standardized meditation programs: Mindfulness-Based Stress Reduction (MBSR) and Compassion Cultivation Training (CCT) delivered in a retreat format with a cross-over design in a general population sample of healthy adults.

NCT ID: NCT05131334 Completed - Alcohol Withdrawal Clinical Trials

Auricular Vagal Stimulation in Alcohol Craving

VNS_CRAV
Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Background: The cause of the vegetative symptoms is a sympathetic driven misbalance of the autonomous nervous system. To restore vegetative balance in alcohol withdrawal syndrome new neuro-modulatory methods, such as percutaneous auricular vagal stimulation (pVNS) could be used. Measuring the pupil size is a suitable method to assess imbalances or dysfunctions of the vegetative regulation in individuals. Objective: The objective of this study is to assess the pupil reaction to the cholinergic antagonist tropicamide in alcohol withdrawal syndrome as a biomarker of the vegetative balance before and after pVNS. Methods: 30 patients aged between 20 and 65 were recruited in this open-label, controlled pilot trial with repeated measure design. pVNS was administered at the left cymba conchae for 72 hours with intermitted stimulation. Pupillometric recording lasted about 60 min and was performed at baseline and following pVNS. The reaction of the pupil to an anticholinergic agent was measured as a receptor-test in terms of a psychophysiological feedback mechanism to pVNS.

NCT ID: NCT03920241 Completed - Clinical trials for Psychological Distress

Cognition and Emotion in Meditation: A Comparison Between Mindfulness and Compassion Standardized Programs

Start date: May 1, 2017
Phase:
Study type: Observational

The study is aimed at comparing the differential effects of two widely used standardized meditation programs: Mindfulness-Based Stress Reduction (MBSR) and Compassion Cultivation Training (CCT) in general population samples. To address this goal, the effects will be measured by self-report questionnaires belonging to different domains (mindfulness, compassion, well-being, psychological distress, and psychological functioning) as well as information processing measures (i.e., Attentional Blink), and psychophysiological measures (EEG and EKG). Changes will be assessed immediately after finishing the 8-week programs and through several inter-session assessments. Data analysis will include the mean change scores differences, as well as novel network analysis procedures to assess topological reorganization of constructs derived from the programs.