Can a Novel Manual Therapy Technique Help Relieve Stress? Assessing

Status Not yet recruiting

Clinical Trial Summary

Stress, when left unmanaged, can have detrimental effects on both physical and mental health, contributing to conditions such as high blood pressure, anxiety, and even cardiovascular disease. Effective stress management therapies may help maintain overall well-being and reduce the risk of long-term health complications. The Primal Reflex Release Technique (PRRT) is a novel manual therapy that may reduce markers related to stress such as heart rate variability (HRV) and patient-reported outcomes (PROs). Therefore, the purpose of this study is to elucidate the potential for PRRT to improve HRV and PROs.

Clinical Trial Description

This randomized, controlled experimental intervention study evaluates acute impacts of a reflex-targeted manual therapy called Primal Reflex Release Technique (PRRT) on cardiovascular indices of stress and sympathetic tone. After consenting and baseline characteristics, subjects are allocated to receive either the PRRT or the control condition. Continuous electrocardiography (ECG) and impedance cardiography (ICG) monitoring will be used to track heart rate variability (HRV) changes across three phases: 1. Pre-intervention during a 5-minute video of aquatic nature scenes to establish resting baseline 2. 5 minutes of a practitioner administering targeted spinal manipulation PRRT protocol in the treatment group to stimulate innate protective reflexes OR continued relaxation video viewing for control group 3. Post-intervention repeat of the standardized video to assess changes after PRRT session without ongoing manipulation The PRRT targets precise anatomical locations and neural pathways including stimulating facial muscles, upper spinal reflexes and traction of the suboccipital muscles. Brief, reversible sensations will occur without expected harm or lasting effects. Psychological state assessed via paper mood scales pre/post tracks subjective stress correlates. Analysis using linear mixed effects models contrast whether indices of cardiovascular reactivity and psychological responses shift acutely with PRRT versus control video. Findings could provide physiological validation for integration as stress-alleviating treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06305585
Study type	Interventional
Source	University of Idaho
Contact	Nickolai J Martonick, PhD
Phone	(208) 885-8749
Email	nmartonick@uidaho.edu
Status	Not yet recruiting
Phase	N/A
Start date	March 2024
Completion date	March 2025

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04680611` - Severe Asthma, MepolizumaB and Affect: SAMBA Study
Completed	`NCT05703087` - Positive Cueing in Knee Arthroplasty.	N/A
Completed	`NCT02629016` - Stress Reduction: A Pilot Study With Adolescents	N/A
Completed	`NCT02541240` - Effects of an Intervention to Enhance Resilience in Physical Therapy Students	N/A
Completed	`NCT01406028` - Does Emotional Support Decrease In Vitro Fertilization Stress?	N/A
Completed	`NCT00121160` - Health SMART (Stress Management and Relaxation Training) to Improve Vaccine Immune Response	Phase 1
Completed	`NCT02621775` - Effectiveness of Two Stress Management Programs in Adaptation Disorder With Anxiety (ADA)	N/A
Recruiting	`NCT04474418` - Psychometric Characterization of Patients With Cardiac Arrhythmias
Completed	`NCT03310112` - Mindfulness Training in U.S. Army Cohorts	N/A
Terminated	`NCT03893617` - Brief Stresses Experimental Study	Phase 1
Active, not recruiting	`NCT05542498` - Promoting Stress Management and Engagement in Introductory Physics Courses With Mindfulness and Relaxation	N/A
Completed	`NCT02394899` - Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease	N/A
Terminated	`NCT00962273` - The Pandemic Stress Vaccine: A Resource to Enhance the Resilience of Healthcare Workers Facing an Infectious Outbreak	N/A
Completed	`NCT00451126` - Moderating Impact of Various Emotion Personality Factors on Salivary Cortisol Response to a TSST	N/A
Completed	`NCT06051500` - Psychological and Physiological Effects of Different Objects of Breath Meditation	N/A
Completed	`NCT02801045` - Art Therapy in Palliative Care: Study of Identification and Understanding of the Mechanisms of Change in the Patient	N/A
Completed	`NCT03308344` - Mindfulness Training in Military Spouses	N/A
Recruiting	`NCT06029348` - Cerebrovascular Health and Resilience in Midlife	N/A
Completed	`NCT05869006` - The Effect of Designed SIA Instrument Supported Interpersonal Relations-Based Group Practice on Psychological Well-Being and Creativity	N/A
Completed	`NCT04484649` - Sleeping Healthy/Living Healthy Development	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Can a Novel Manual Therapy Technique Help Relieve Stress? Assessing Effects of Primal Reflex Release on the Body's Stress Response

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms