Prevalence of Sonographic Abnormalities of Joints and Entheses in Psoriasis Patients With or Without Musculoskeletal Complains

Psoriasis Clinical Trial

— EchoPso  

Official title:

Prevalence of Sonographic Abnormalities of Joints and Entheses in Patients With Psoriasis With or Without Musculoskeletal Complains

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04074070
• Other study ID #: APHP190683
• Secondary ID: 2018-A02781-54
• Status: Completed
• Start date: February 18, 2020
• Est. completion date: September 30, 2020

Study information

• Verified date: March 2023
• Source: Assistance Publique - Hôpitaux de Paris
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The objectives of this study are: - to estimate the prevalence and severity of inflammatory (synovitis, tenosynovitis, enthesitis, dactylitis) and structural (erosions, osteophytes, enthesophytes, cortical irregularities ) ultrasound lesions in psoriasis patients with or without related musculoskeletal symptoms; - to compare them to healthy subjects or patients suffering from rheumatoid arthritis and osteoarthritis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: September 30, 2020
• Est. primary completion date: September 30, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age = 18 years;
• Psoriasis diagnosed by a dermatologist;
• Able to participate in the study;
• Informed consent signed.

Exclusion Criteria:

• Chronic disease likely to cause musculoskeletal symptoms (connective tissue diseases, inflammatory bowel diseases, overload disorders, crystal related arthritis, septic arthritis...).

Related Conditions & MeSH terms

• Psoriasis

Intervention

Other:
• Ultrasound examination
Ultrasound examination of joints, tendons and entheses.

Locations

Country	Name	City	State
France	Rheumatology Department, Ambroise Paré Hospital	Boulogne-Billancourt

Sponsors (1)

Lead Sponsor	Collaborator
Assistance Publique - Hôpitaux de Paris

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	synovitis	Number and percentage, N (%) of patients with at least one synovitis.	through study completion, an average of 1 year
Primary	enthesitis	N (%) of patients with at least one ultrasound enthesitis.	through study completion, an average of 1 year
Primary	joint erosion	N (%) of patients with at least one joint erosion.	through study completion, an average of 1 year
Primary	osteophyte/ cortical irregularity	N (%) of patients with at least one osteophyte/ cortical irregularity.	through study completion, an average of 1 year
Primary	enthesophyte	N (%) of patients with at least one enthesophyte.	through study completion, an average of 1 year