Psoriasis Clinical Trial
Official title:
Clinical Research on Treatment of Psoriasis by Human Umbilical Cord-derived Mesenchymal Stem Cells
To evaluate the effect and safety of treatment of psoriasis by human umbilical cord-derived mesenchymal stem cel
Psoriasis is a chronic and recurrent inflammatory skin disease and its histological features
are characterized by epidermal hyperplasia, increased angiogenesis and immune cell
infiltration. Psoriasis prevalence is about 0.1%-3%, affecting approximately 125 million
people worldwide. In China, there are about 10 million psoriasis patients.
Human umbilical cord-derived MSC (huc-MSC) has many advantages for the treatment of immune
disease. Because it was demonstrated that huc-MSCs are effective in modulating immune cells
and treating diseases and it has low immunogenicity. Furthermore, huc-MSCs do not raise
ethical issue for clinical applications.
Some experimental results and cases has showed that mesenchymal stem cell (MSC) can prevent
or treat psoriasis. This clinical study is conducted to provide more data to evaluate the
effect and safety of treatment of psoriasis by human umbilical cord-derived mesenchymal stem
cell.
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