Psoriasis Clinical Trial
Official title:
A Randomised, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study Evaluating The Safety/Tolerability, Pharmacokinetic and Pharmacodynamic Effects of UCB5857 in Healthy and Mild-to-Moderate Psoriatic Subjects
To evaluate the safety and tolerability of UCB5857. Part 1 of the study explores single doses of the drug. Part 2 of the study explores giving the drug every day for 14 days. The study uses healthy and psoriasis subjects.
This is a first-in-human (FIH), Phase 1, randomized, double-blind, placebo controlled,
single center study designed to evaluate the safety/ tolerability, pharmacokinetics (PK),
and pharmacodynamics (PD) of UCB5857 following oral administration of single ascending doses
(SAD) in healthy subjects (Part 1) and multiple ascending doses (MAD) in healthy and
mild-to-moderate psoriatic subjects (Part 2).
The primary objective of this study is to investigate the safety and tolerability of UCB5857
when given as single oral doses in healthy subjects and as ascending multiple oral doses in
healthy subjects and mild-to-moderate psoriatic subjects.
;
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science
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