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Psoriasis clinical trials

View clinical trials related to Psoriasis.

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NCT ID: NCT01208090 Completed - Psoriasis Clinical Trials

ACT-128800 in Patients With Moderate to Severe Chronic Plaque Psoriasis

Start date: October 31, 2010
Phase: Phase 2
Study type: Interventional

This study will assess the efficacy, safety and tolerability of two doses of ACT 128800 in patients with moderate-to-severe chronic plaque psoriasis.

NCT ID: NCT01206660 Completed - Psoriasis Clinical Trials

Effects of Desoximetasone Spray 0.25% in Patients With Moderate to Severe Plaque Psoriasis

Start date: August 2010
Phase: Phase 3
Study type: Interventional

The objective of this study is to demonstrate that desoximetasone 0.25% topical spray is effective for the treatment of patients with moderate to severe plaque psoriasis.

NCT ID: NCT01206387 Completed - Psoriasis Clinical Trials

Effects of Desoximetasone Spray 0.25% on Moderate to Severe Plaque Psoriasis

Start date: August 2010
Phase: Phase 3
Study type: Interventional

The objective of this study is to demonstrate that desoximetasone 0.25% topical spray is effective for the treatment of patients with moderate to severe plaque psoriasis.

NCT ID: NCT01205880 Completed - Psoriasis Clinical Trials

Study to Evaluate Vectical in Combination With Clobex Spray to Treatment Plaque Psoriasis

Start date: December 2009
Phase: Phase 4
Study type: Interventional

This investigator-blinded study is designed to assess whether the order of application affects the efficacy of the combination treatment Clobex® Spray (clobetasol propionate) and Vecitcal® (calcitriol) Ointment in plaque psoriasis.

NCT ID: NCT01202565 Completed - Clinical trials for Moderate to Severe Plaque Psoriasis

Effectiveness of Adalimumab (HUMIRA®) in the Treatment of Scalp and Nail Affection in Patients With Moderate to Severe Plaque Psoriasis in Routine Clinical Practice

Start date: September 2010
Phase: N/A
Study type: Observational

There is clearly a need for further data on the efficacy of biologic agents in the treatment of nail and scalp psoriasis, especially in the routine clinical setting. A few case reports can be found, but no published data exists from non-interventional studies, such as post-marketing observational studies (PMOS) that reflect routine clinical practice. The aim of this PMOS is to evaluate the long-term (12-month) efficacy of adalimumab in the treatment of nail and scalp psoriatic lesions in routine dermatologic practice.

NCT ID: NCT01197976 Completed - Clinical trials for Palmoplantar Psoriasis

Efficacy Study of TEPSO® Socks in Improving Palmoplantar Psoriasis

Start date: March 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy of a special sock, manufactured using TEPSO®, compared to a normal cotton sock in the prognosis of symmetrical palmoplantar psoriasis present for at least one year.

NCT ID: NCT01195831 Completed - Scalp Psoriasis Clinical Trials

Efficacy and Safety of Xamiol® Gel Compared to Calcipotriol Scalp Solution in Patients With Scalp Psoriasis

Start date: September 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the clinical efficacy of once daily treatment for 4 weeks with Xamiol® gel (calcipotriol plus betamethasone) with twice daily treatment for 4 weeks with Calcipotriol Scalp Solution in patients with scalp psoriasis.

NCT ID: NCT01194219 Completed - Plaque Psoriasis Clinical Trials

Study to Evaluate Safety and Effectiveness of Oral Apremilast (CC-10004) in Patients With Moderate to Severe Plaque Psoriasis

ESTEEM 1
Start date: September 9, 2010
Phase: Phase 3
Study type: Interventional

This study evaluated the effects of an called apremilast. Apremilast works by lowering some of the chemicals that affect psoriasis and therefore improves the symptoms of psoriasis. The purpose of this study was to test apremilast and compare its effects to placebo (an inactive substance which contains no medicine but is in the same form as the drug). This study was able to test for efficacy (improvement of signs and symptoms) and safety of apremilast in patients with moderate to severe psoriasis.

NCT ID: NCT01188928 Completed - Psoriasis Vulgaris Clinical Trials

LEO 80185 in the Treatment of Psoriasis Vulgaris on the Non-scalp Regions of the Body (Trunk and/or Limbs)

Start date: September 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of Calcipotriol 50 Mcg/g Plus Betamethasone 0.5 mg/g (as Dipropionate) Topical Suspension with the active components when used individually as monotherapy in the topical suspension vehicle (betamethasone dipropionate in the topical suspension vehicle, calcipotriol in the topical suspension vehicle) and with the topical suspension vehicle alone in the treatment of psoriasis vulgaris on the non-scalp regions of the body (trunk and/or limbs) in a large phase 3 study. This comparison will ensure a more informed assessment of the benefit/risk ratio of Calcipotriol 50 Mcg/g Plus Betamethasone 0.5 mg/g (as Dipropionate) Topical Suspension while also establishing the optimal treatment duration in psoriasis vulgaris on the non-scalp regions of the body (trunk and/or limbs).

NCT ID: NCT01187264 Completed - Psoriasis Clinical Trials

Dose Ranging Study to Compare the Efficacy and Safety of Methotrexate in Plaque Type Psoriasis

Start date: August 2008
Phase: Phase 4
Study type: Interventional

In this study the investigators intend to compare the efficacy and safety of two fixed doses of once weekly oral methotrexate in a prospective randomized double blind manner in patients with severe plaque type psoriasis.