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Psoriasis clinical trials

View clinical trials related to Psoriasis.

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NCT ID: NCT02547714 Completed - Plaque Psoriasis Clinical Trials

Open-label Study of Subcutaneous Secukinumab to Evaluate Efficacy and Safety in Patients With Plaque Psoriasis Who Had Inadequate Response to Cyclosporine A

Start date: June 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of secukinumab at Week 16 based on psoriasis area and severity index (PASI) 75 in subjects who had inadequate response to cyclosporine A.

NCT ID: NCT02538341 Completed - Clinical trials for Rheumatoid Arthritis

Safety and Effectiveness of Live Zoster Vaccine in Anti-Tumor Necrosis Factor (TNF) Users (VERVE Trial)

Start date: May 2016
Phase: Phase 2
Study type: Interventional

The VaricElla zosteR VaccinE (VERVE) trial evaluates the safety and effectiveness of the Herpes zoster (HZ) vaccine for shingles, Zostavax, in patients over 50 years old with arthritis and other diseases who are using anti-tumor necrosis factor (TNF) therapy and who have not previously received the vaccine.

NCT ID: NCT02534636 Completed - Healthy Subjects Clinical Trials

Safety Study of BMS-986165 in Healthy Subjects and to Treat Psoriasis

Start date: October 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to establish if BMS-986165 is safe and effective at treating autoimmune diseases. BMS-986165 which has shown some promise in preclinical studies for inhibiting autoimmune conditions. This study will be the first time this drug is given to humans, and will be conducted entirely in healthy subjects. It will be run in 4 Parts. Part A will investigate single oral doses of drug. Part B will investigate giving the drug daily for 14 days. Part C will investigate daily doses for 14 days in healthy volunteers with Japanese decent. Part D will investigate whether food, stomach acidity or giving the drug in a capsule makes a difference to the safety and potential use of this drug.

NCT ID: NCT02533973 Completed - Psoriasis Vulgaris Clinical Trials

Long-term Treatment of Scalp Psoriasis With Xamiol® Gel in a Large Adult Chinese Population

Start date: September 2015
Phase: Phase 4
Study type: Interventional

A phase 4 trial comparing the safety and efficacy of treatment with Xamiol® gel (calcipotriol 50 mcg/g plus betamethasone 0.5 mg/g (as dipropionate)) once daily (as required) with Daivonex® scalp solution (calcipotriol 50 mcg/g) twice daily (as required) in Chinese subjects with scalp psoriasis

NCT ID: NCT02533375 Completed - Adalimumab Clinical Trials

Study to Investigate Efficacy and Safety of Adalimumab in Japanese Subjects With Generalized Pustular Psoriasis (GPP)

Start date: September 28, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study was to investigate the efficacy, safety, and pharmacokinetics of adalimumab in Japanese participants with generalized pustular psoriasis (GPP) who did not have an adequate response to their currently approved treatment.

NCT ID: NCT02529956 Completed - Clinical trials for Mild to Moderate Psoriasis

A Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of UCB4940 in Patients With Psoriasis

Start date: November 2012
Phase: Phase 1
Study type: Interventional

To evaluate the safety of UCB4940 administered by iv infusion of a single ascending dose in subjects with mild to moderate plaque psoriasis.

NCT ID: NCT02518048 Completed - Clinical trials for Skin and Connective Tissue Diseases

A Psoriasis Plaque Test Trial With LEO 90100 Compared to Betesil® in Patients With Psoriasis Vulgaris

Start date: August 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the anti-psoriatic effect of LEO 90100 aerosol foam compared with Betesil® medicated plaster

NCT ID: NCT02515097 Completed - Plaque Psoriasis Clinical Trials

Safety and Efficacy of IDP-122 in the Treatment of Participants With Plaque Psoriasis

Start date: November 5, 2015
Phase: Phase 3
Study type: Interventional

This study is to evaluate the safety and efficacy of a topical lotion when applied once daily to adult participants with moderate to severe plaque psoriasis (defined as an Investigator's Global Assessment [IGA] score of 3 or 4).

NCT ID: NCT02514694 Completed - Psoriasis Vulgaris Clinical Trials

LEO 32731 - A Phase I Study in Healthy Subjects

Start date: July 2015
Phase: Phase 1
Study type: Interventional

LEO 32731 ("Study Drug") is an investigational drug which is being developed by LEO Pharma A/S ("the Sponsor") for treatment of psoriasis. The aim (s) of this Study are to determine: - The safety and tolerability of the Study Drug and any side effects that might be associated with it - The Study will also measure how much of the Study Drug that gets into the blood and how long time it takes for the body to remove it.

NCT ID: NCT02514577 Completed - Plaque Psoriasis Clinical Trials

Safety and Efficacy of IDP-122 in the Treatment of Participants With Plaque Psoriasis

Start date: November 7, 2015
Phase: Phase 3
Study type: Interventional

This study is to evaluate the safety and efficacy of a topical lotion when applied once daily to adult participants with moderate to severe plaque psoriasis (defined as an Investigator's Global Assessment [IGA] score of 3 or 4).