Correction of Psoriatic T Cell Signatures by Deucravacitinib

Status Not yet recruiting

Clinical Trial Summary

This study aims to assess cutaneous and blood immune cell function of patients with psoriasis before and after initiation of treatment with the Tyrosine kinase 2 (TYK2) blocker, deucravacitinib.

Clinical Trial Description

This is a one-arm, open-label study to examine the effect of deucravacitinib on cutaneous and blood immune cells of psoriatic patients. 25 subjects with moderate to severe psoriasis will be enrolled. Biopsy and blood samples will be collected before and during treatment and undergo molecular profiling to assess for deucravacitinib-corrected signatures. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05858645
Study type	Interventional
Source	University of California, San Francisco
Contact	Raymond Cho, MD, PhD
Phone	415 575 0524
Email	rashes@ucsf.edu
Status	Not yet recruiting
Phase	Phase 4
Start date	July 2023
Completion date	June 2026

View Details

See also
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