Predicting Inflammatory Skin Disease Response to IL-23 Blockade

Status Recruiting

Clinical Trial Summary

This study examines the effect of IL-23 blockade with Tildrakizumab on the immune cells of psoriatic skin lesions.

Clinical Trial Description

This is a one-arm, open-label study to examine the effect of Tildrakizumab. Tildrakizumab is a FDA-approved medication for the treatment of cutaneous psoriasis. This study will examine how Tildrakizumab affects immune cells within psoriatic skin lesions. Fifteen subjects with moderate to severe psoriasis will be enrolled. Biopsy samples will be collected and undergo molecular profiling to correlate profiles with and to predict Tildrakizumab treatment response. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04541329
Study type	Interventional
Source	University of California, San Francisco
Contact	Jeffrey Cheng, MD, PhD
Phone	415-575-0524
Email	rashes@ucsf.edu
Status	Recruiting
Phase	Phase 4
Start date	September 16, 2020
Completion date	September 9, 2024

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